Pemphigus vegetans is a clinical variant of pemphigus vulgaris, accounting for 1-2% of all very rare pemphigus cases in children. The involvement of the oral mucosa in this disease is usually accompanied by severe pain that aggravates the patient's malnourished condition. Conversely, malnutrition may also reduce vulnerability towards autoimmune diseases. Although pemphigus vegetans has never be...

Objective: Pemphigus vulgaris, a fatal autoimmune mucocutaneous disorder commonly seen involving the oral cavity, has since a long time remained a topic of concern regarding its treatment modalities. Pulse therapy, introduced in 1984, employs high-dose corticosteroids along with certain immunosuppressive agents and has gained wide popularity since the last three decades due to its advantage of ...

anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. our objective was to assess the value of elisa in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris. based on clinical presentation and histopathologic confirmation for the diagnosis of the pemphigus, 38 patients took part in the study. sera of the patients were te...

Introduction: The treatment of oral mucosal disorders must be based on an early and correct diagnosis. Pemphigus vulgaris (PV) and mucous membrane pemphigoid (MMP) are among the diseases that pose the greatest diagnostic difficulties for dentists, with scores of 7.35 and 8.03, respectively, on a scale from 0-10. Objective: To conduct a literature review on PV and MMP, and to summarize the case ...

introduction : pemphigus comprises a group of diseases characterized by cutaneous and mucosal blistering. pemphigus vulgaris (pv) is the most common and important variant. recent reports have revealed the relatively high incidence of pv in iran. the onset or aggravation of many human diseases is attributed to oxidative stress and it has been suggested as one of the several factors responsible f...