Acute intermittent porphyria (AIP) is an autosomal dominant genetic defect in heme synthesis. Patients with this illness can have episodic life-threatening attacks characterized by abdominal pain, neurological deficits, and psychiatric symptoms. Feigning this illness has not been reported in the English language literature to date. Here, we report on a patient who presented to the hospital with...

In the first British study to investigate systematically what happens to opiate addicts after treatment 50 opiate addicts admitted for inpatient treatment of their drug dependence were followed up for six months after discharge. All had been withdrawn from opiates before follow up. Six months later 26 were not using opiates: 12 had not used opiates at any time since discharge. When subjects in ...

introduction: studies have shown that opiates cause disorders in fertilization and accessory reproductive glands in animals. on the other hand studies have shown important role of glycoconjugates in sperm epididymal maturation. lectins can detect glycoconjugates with specific terminal glucose molecules. therefore this study was conducted to assess the possible effects of opiates on these import...

background: to measure suspected abuse of the methamphetamine (ma) among methadone maintenance treatment (mmt) patients in tehran, we studied all 206 patients who were admitted to mmt program from 2009 to 2015 to andishe-no addiction treatment clinic.  methods: ma presence was screened in one of the random urine samples routinely taken for tests of other drugs.  results: 70 (34.3%) patients wer...

BACKGROUND The diagnosis of anaphylactic reactions due to opiates during anaesthesia can be difficult, since in most cases various drugs may have been administered. Detection of specific IgE to poppy seed might be a marker for sensitisation to opiates in allergic people and heroin-abusers. This study assessed the clinical value of morphine, pholcodine and poppy seed skin-prick and IgE determina...

Although opiates can provide patients with relief from pain and the discomfort of cough, the routine prescription of these drugs for infants demands caution and concern. Infants, particularly neonates, are not merely small adults requiring smaller dosages, but rather uniquely different patients. Neonates present with an immature physiology and biochemistry with respect to drug metabolism. We re...