BACKGROUND Delaitre and Maignien performed the first successful laparoscopic splenectomy in 1991. After that, laparoscopic splenectomy has become one of the most frequently performed laparoscopic solid organ procedures. AIM To demonstrate the surgical techique of laparoscopic splenetomy with reduced portals. METHODS A reduce port laparoscopic splenectomy was performed by using a 10 mm and t...

OBJECTIVES Encouraging progress has been made in application of splenectomy in the treatment of relapsed hemophagocytic lymphohistiocytosis (HLH) of unknown cause. The aim was to determine the roles of lymphocyte subpopulations and inflammatory cytokines in splenectomy. METHODS We retrospectively analyzed changes in lymphocyte subpopulations and levels of inflammatory cytokines at different t...

Laparoscopic splenectomy has universal acceptance due to less morbidity and decreased incidence of peroperative and postoperative complication. It is not a popular procedure in Pakistan due to technical challenges. Here, we are presenting our experience of laparoscopic splenectomy for haematological disorders at Aga Khan University Hospital. A total of seven cases, underwent elective laparoscop...

BACKGROUND In hereditary spherocytosis with severe anemia, splenectomy is a recommended treatment. However, the spleen carries an important role both in immune function and coagulation. The increased risk of bacterial infections associated with splenectomy is well known. Recently, hypercoagulation disorders have also been linked to splenectomy through loss of regulation of platelet activity, lo...

abstract introduction: thalassemia is the most common hereditary anemia in iran. the aim of this study was to evaluate the humoral immune system and assess the effect of splenectomy on the serum level of immunoglobulins igg, igm, and iga and complement components in patients with major thalassemia. materials and methods: this interventional semi-experimental study (before-after) was performed o...

Spleen is a major component of the reticuloendothelial system and functions as a filtering system for the encapsulated bacteria especially in children. Knowing the spectrum of conditions leading to splenectomy in any geographic area is important to decrease the number of unnessesary splenectomies. Here we report the causes of splenectomy in three major general referring hospitals in Shiraz, ...

malaria is a major problem in tropical and sub-tropical countries, with high morbidity and mortality. splenectomy makes patients more susceptible to serious bacterial and parasitic infections. we report for the first time in iran a fatal case of plasmodium vivax malaria, confirmed by microscopic and molecu­lar (semi-nested multiplex pcr) tests in a patient who had undergone splenectomy due to h...

PURPOSE Single-port laparoscopic splenectomy has been performed sporadically. The aim of this study is to assess our experience with single-port laparoscopic splenectomy compared to conventional multiport laparoscopic surgery for the usual treatment modality for various kinds of splenic disease. METHODS Between October 2008 to February 2014, 29 patients underwent single-port laparoscopic sple...

OBJECTIVE Non-operative management of blunt splenic injury in adults has been applied increasingly at the end of the last century. Therefore, the lifelong risk of overwhelming post-splenectomy infection has been the major impetus for preservation of the spleen. However, the prevalence of posttraumatic infection after splenectomy in contrast to a conservative management is still unknown. Objecti...