Avascular osteonecrosis of the femoral head (ONFH) is one causes hip pain that clinicians need to know about. In many cases, it a fortuitous discovery when pelvic X-rays performed for another reason. other reveals disease. For rheumatologist, major part job look cause. An etiology can be found ONFH in about 70% cases. Some them are evident and context give diagnosis (corticosteroids, alcohol ab...

Approximately 25,000 patients undergo renal transplantation every year worldwide due to end-stage renal disease(ESRD). Renal transplantation is expected to lead to a progressive correction of the established renal bone disease, and osteonecrosis of the femoral head(ONFH) is a common and severe complication in these patients. It induces deformity of the hip joint and reduces the quality of life,...

INTRODUCTION The purpose of this prospective cohort study was to compare the surgical treatment of non-ONFH in adulthood by curettage and bone grafting with treatment by curettage and bone grafting in combination with invasive electromagnetic field treatment using Magnetodyn(®). This was assessed by examining whether electromagnetic field treatment has a positive additive effect on the clinical...

PURPOSE There are no reports about bone graft and cell therapy for the osteonecrosis of femoral head (ONFH). We prospectively evaluated the clinical results of auto-iliac cancellous bone grafts combined with implantation of autologous bone marrow cells for ONFH. MATERIALS AND METHODS Sixty-one hips in 52 patients with ONFH treated with bone graft and cell therapy were enrolled, and the averag...

Glucocorticoid has been reported to decrease blood vessel number and harm the blood supply in the femoral head, which is recognized to be an important mechanism of glucocorticoid-induced osteonecrosis of the femoral head (ONFH). To prevent glucocorticoid-induced ONFH, medication that promotes both bone formation and angiogenesis would be ideal. Vitamin K2 has been revealed to play an important ...

BACKGROUND Although numerous studies describe the clinical characteristics of idiopathic osteonecrosis of the femoral head (ONFH) in specific study populations, these have not been confirmed in countrywide studies. QUESTIONS/PURPOSES We therefore determined: (1) the annual number of patients seeking medical care and number of patients newly diagnosed; and (2) the distribution of the age and g...

BACKGROUND Osteonecrosis is an incapacitating disorder with high morbidity. Though extracorporeal shockwave therapy (ESWT) provides a noninvasive treatment option, controversial subjects still exist about its effectiveness, indications, and mechanism of action. METHODS An electronic databases search was performed using PubMed, Embase, and the Cochrane library to collect clinical trials, case ...

Osteonecrosis of the femoral head (ONFH) can be caused by a decrease in the activity or numbers of osteoblasts, a process in which apoptosis may play an essential role. We investigated the effect of dexamethasone (Dex) combined with hypoxic stress on murine osteoblastic MC3T3-E1 cells. Flow cytometry, western blot and real-time quantitative PCR analyses revealed that hypoxia significantly enhan...

To explore the clinical characteristics of steroid-associated osteonecrosis of the femoral head (ONFH) presenting initially normal magnetic resonance imaging (MRI) results.This retrospective study examined data from 23 cases that suffered from ONFH but presented a normal image at the first MRI examination after corticosteroid therapy from June 2005 to December 2013. Data on protopathy, age, sex...

BACKGROUND The aim of this study was to contrast the collapse values of the postoperative weight-bearing areas of different tantalum rod implant positions, fibula implantation, and core decompression model and to investigate the advantages and disadvantages of tantalum rod implantation in different ranges of osteonecrosis in comparison with other methods. MATERIAL AND METHODS The 3D finite el...