Pathologic processes in glaucoma include increased apoptosis, accumulation of extracellular material in the trabecular meshwork and optic nerve, condensations of the cytoskeleton and precocious cellular senescence. Oxidative stress was shown to generate these alterations in primary ocular cells. Fatty acids omega-3 and -6 are alleged to constitute a prophylaxis against these deleterious effects...

OBJECTIVE The objective of this study was to review and evaluate published evidence on the use of omega-3 fatty acid in the prevention and treatment of atrial and ventricular arrhythmias. Postulated mechanisms of the antiarrhythmic effects of omega-3 fatty acid are discussed. DATA SOURCES Peer-reviewed articles/abstracts published in English language were identified from MEDLINE and Current C...

a 42-d study was conducted to evaluate the influence of full-fat flaxseed (fs) and canola seed (cs) on broiler performance, fatty acid (fa) profile of meat, and the oxidative stability of meat during frozen storage. a total of 324 one-day old broiler chicks were randomly attributed to 6 experimental groups and fed iso-energetic and isonitrogenous diets as follows, c: control (soybean-corn); cs1...

Metabolic endotoxemia, commonly derived from gut dysbiosis, is a primary cause of chronic low grade inflammation that underlies many chronic diseases. Here we show that mice fed a diet high in omega-6 fatty acids exhibit higher levels of metabolic endotoxemia and systemic low-grade inflammation, while transgenic conversion of tissue omega-6 to omega-3 fatty acids dramatically reduces endotoxemi...

background: dietary risk factors constitute some of the leading risk factors for cardiovascular disease in iran. the current study reports the burden of ischemic heart disease (ihd) attributable to a low omega-3 fatty acids intake in iran using the data of the global burden of disease (gbd) study 2010. methods: we used data on iran for the years 1990, 2005, and 2010 derived from the gbd study c...

Free fatty acids and the risk of sudden death • Elevated circulating free fatty acids have been reported to be a risk factor for sudden death. In the Paris Prospective Study reported by Jouven et al. [ 3 ], 5250 men were observed over a mean follow-up period of 22 years. The concept that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) may have potential health benefits has been supported by e...

Recent evidence demonstrates that age and disease-related decline in cognition depends not only upon degeneration in brain structure and function, but also on dietary intake and nutritional status. Memory, a potential preclinical marker of Alzheimer's disease, is supported by white matter integrity in the brain and dietary patterns high in omega-3 and omega-6 polyunsaturated fatty acids. Howeve...