Experimental studies have reported that the amyloid-β proteins can form pores in cell membranes, and this could be one possible source of toxicity Alzheimer's disease. Dissociation these therefore a potential therapeutic approach. It is known high photon density free-electron laser experiments laser-induced nonequilibrium molecular dynamics simulations (NEMD) dissociate amyloid fibrils at speci...

To go beyond polyethylene oxide in lithium metal batteries, a hybrid polymer/oligomer cell design is presented, where an ester oligomer provides high ionic conductivity of 0.2 mS cm−1 at 40 °C within thicker composite cathodes with active mass loadings up to 11 mg cm−2 (LiNbO3-coated) LiNi0.6Mn0.2Co0.2 (NMC622), while 30 µm thin scaffold-supported polymer electrolyte affords mechanical stabilit...

Background The specific pathological findings in Alzheimer’s disease (AD) brain are senile plaques composed of amyloid-β protein (Aβ) and neurofibrillary tangles (NFTs) highly phosphorylated tau protein. It has been suggested that autophagy may play an important role the degradation proteins. In this study, we investigated whether is involved oligomeric by immunohistochemistry using autopsied A...