(2015) Harvesting of olfactory ensheathing cells for autologous transplantation into the spinal cord injury. Its complexity in dogs. The mucosa lining the nasal cavity and its content contains olfactory sensory neurons (OSNs). The OSNs are organized into different territories (four in mammals with a more sophisticated model) and, with the exception of the OSNs enclosed in the vomeronasal organ,...

Background: There are recent evidence of sleep-dependent changes in olfactory system structure and function which contribute to odor memory perception. Objective: The aim the present study is effect elimination mucosa on electrical activity hippocampus, bulb, tubercle, pyriform cortex frontal during wakefulness sleep. Methodology: Fifteen adult armadillos chronically prepared for electrographic...

Ultrafine particles (UFP, particles <100 nm) are ubiquitous in ambient urban and indoor air from multiple sources and may contribute to adverse respiratory and cardiovascular effects of particulate matter (PM). Depending on their particle size, inhaled UFP are efficiently deposited in nasal, tracheobronchial, and alveolar regions due to diffusion. Our previous rat studies have shown that UFP ca...

Subjects were trained to identify by assigned number common substances presented as vapor phase stimuli via an orthonasal or a retronasal route. Following training, odorant identification learning was evaluated by measuring ability to correctly identify to a criterion. Those who met the criterion were then tested first with the stimuli presented to the nares that differed in location from the n...

introduction: spinal cord injuries (sci) lead to permanent irreversible functional deficits.  poor prognosis of patients is the motivation of searching a treatment for the chronic injury.  planting stem cells provides us with a promising strategy. in the meanwhile, the use of olfactory ensheathing cells (oecs) has shown very good results.  this study aims at evaluating the effect of transplante...

The tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN) both induce nasal tumors in rats and have a common metabolic activation pathway leading to pyridyloxobutylation of DNA. The role of DNA pyridyloxobutylation in rat nasal carcinogenesis has not been evaluated previously. In this study, we used gas chromatography-mass spectrometr...

Following unilateral olfactory bulbectomy in rats the ipsilateral olfactory neuroepithelium undergoes degeneration. Subsequently, the receptor neuron complement of the tissue is restored by the proliferation and differentiation of immature neuroblasts. However, as noted by other workers, in the absence of a target organ the dynamics of neuron regeneration is altered such that there is an overal...

Abstract Noses are extremely sophisticated chemical detectors allowing animals to use scents interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating mucosa. Different odorants, or different concentrations same odorant, activate unique ensembles ORs. This mechanism combinatori...