نتایج جستجو برای: oesophageal carcinoma
تعداد نتایج: 402009 فیلتر نتایج به سال:
OBJECTIVE This study aimed to investigate the validity and feasibility of cervical oesophagostomy as a treatment for patients with severe dysphagia after radiotherapy for nasopharyngeal carcinoma. METHODS The study retrospectively analysed the clinical data, symptoms, physical signs, treatment and outcomes of 12 patients treated with cervical oesophagostomy for severe dysphagia after radiothe...
BACKGROUND Vinorelbine and cisplatin are active against squamous cell oesophageal carcinoma. The purpose of this phase II study was to evaluate the efficacy and safety of vinorelbine plus cisplatin in previously untreated patients with metastatic squamous cell oesophageal carcinoma and to estimate the progression-free survival, overall survival and quality of life (QoL) of the patient populatio...
Oesophageal carcinoma, accounting for approximately 10 deaths per 100,000 people annually, is a major health problem in the United Kingdom.' With many patients presenting with disseminated disease, either manifest or occult, curative treatment is applicable to only a small minority. For the majority of patients palliative relief of dysphagia is the goal of treatment. Clinicians have an ever inc...
Alcohol is a major risk factor for oesophageal squamous cell carcinoma (OSCC), the most prevalent histological subtype of oesophageal cancer (OC) worldwide. The metabolism of alcohol is regulated by specific enzymes whose activity and expression is influenced by genetic polymorphisms. We conducted a systematic review of current epidemiological evidence of the relationship between alcohol intake...
Serum interleukin-12 and interleukin-18 levels in patients with oesophageal squamous cell carcinoma.
UNLABELLED Interleukin-12 (IL-12) and interleukin-18 (IL-18) play an important role as immunomodulatory factors in cancer pathogenesis. THE AIM of the study was analyze changes of serum IL-12 and IL-18 concentrations in oesophageal squamous cell carcinoma patients depending on the progression of cancer. MATERIALS AND METHODS Blood samples were taken from 41 patients with oesophageal cancer: 5...
BACKGROUND For oesophageal cancer there is no effective standard therapy. We studied the feasibility and efficacy of the cisplatin-gemcitabine combination chemotherapy in patients with unresectable oesophageal cancer. PATIENTS AND METHODS Thirty-six chemonaïve patients with unresectable or metastatic oesophageal adenocarcinoma (24) or squamous-cell-carcinoma (12) were treated with cisplatin (...
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