Mini-G proteins are the engineered GTPase domains of Gα subunits. They couple to GPCRs and recapitulate the increase in agonist affinity observed upon coupling of a native heterotrimeric G protein. Given the small size and stability of mini-G proteins, and their ease of expression and purification, they are ideal for biophysical studies of GPCRs in their fully active state. The first mini-G pro...

purpose : to determine the distribution of iris colors in the population of tehran and to assess possible associations between iris color and ocular disorder methods : through a stratified random cluster sampling approach, 160 clusters were selected in different municipality districts of tehran, and the approached households were invited to a clinic. after the initial interview, all participant...

rehabilitation of facial defects is a complex task, requiring an individualized design of the technique for each patient. the disfigurement associated with the loss of an eye may result in significant physical and emotional problems. various treatment modalities are available, one of which is the use of implants. although implant-supported orbital prosthesis has a superior outcome, it may not b...

sulfur mustard, a bifunctional alkylating agent, causes severe eye injury. the injury is a result of late inflammation, which is mediated by prostaglandins. theoretically, inhibition of prostaglandins by reagents such as indomethacine could result in alleviation of clinical adverse effects. in this study, the protective effect of topically applied indomethacine against sulfur mustard toxicity w...

objective the prevalence of syphilis is increasing in the world. although ocular syphilis is not a common presentation of syphilis, it occurs in 2.5 to 5% of patients with tertiary syphilis and less than 1% of patients with untreated late syphilis. patient we report a 58-year-old man presented with a 3-month history of decreased vision. he developed neurosensory detachment, retinitis and panuve...

dirofilariasis is caused by a filariid parasite of the genus dirofilaria. this zoonotic infection is spread by mosquito vector from animal to human. ocular dirofilariasis involving the eye and adnexa is rare. a nodule in the right eye had developed in a 20-year-old soldier from mazandaran province, north of iran. the mass was removed surgically and measured 5x5 mm. the specimen was identified o...

Abstract: The objective of this work was to evaluate the influence pruning management mini-stumps Climax blueberry cultivar, when weekly fertigated, on productivity clonal mini-garden and rooting root vigor mini-cuttings. high survival (100%) production mini-cuttings (182.9 per square meter month) evidence adaptability material successive samplings nutritional conditions provided mini-garden, r...

objective(s): the aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. materials and methods:matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and ph-sensitive polymers which were further filled into an empty hpmc capsule. to asses...