The Dubowitz syndrome is a rare, autosomal recessive disorder including intrauterine growth retardation, craniofacial abnormalities, mental retardation and eczematous skin eruption. Ocular problems occur in about 20%: strabismus, blefarophimosis, ptosis, telecanthus and epicanthal folds being the most frequent ones. We present a three years old girl, diagnosed with Dubowitz syndrome, with sudde...

We report a case of lithium-induced downbeat nystagmus and horizontal gaze palsy in a 62-year-old woman who was treated for a bipolar affective disorder with lithium carbonate for one month. At presentation serum lithium was within therapeutic range. No alternative causes of the ocular motility disturbances were found, and the patient improved significantly as lithium carbonate was discontinued.

The LEOPARD syndrome is a rare, autosomal dominant multisystemic disorder characterized by lentiginosis, ocular hypertelorism, abnormal genitalia, growth retardation, sensorineural deafness, and cardiac and electrocardiographic abnormalities. Although it is not cited, hypertrophic cardiomyopathy is often associated with the disease. In this study, we present a nine-year-old boy with LEOPARD syn...

This article addresses advances in the management of branch retinal vein occlusion - a common retinal vascular disorder in elderly patients which is a significant cause of ocular morbidity. New intravitreal therapies have improved the prognosis for patients, albeit with significant cost implications.

Lambert-Eaton myasthenic syndrome is a rare and acquired autoimmune disorder. We describe two female patients with medial rectus paresis as the only ocular manifestation. After a unilateral medial rectus recession and lateral rectus resection procedure, both patients recovered normal adduction. To our knowledge, this is the first report of surgery for extraocular muscle paresis in Lambert-Eaton...

This study examined the relation between childhood ocular alignment deficits and adult psychiatric outcomes among children at high-risk for schizophrenia and controls. A sample of 265 Danish children was administered a standardized eye exam assessing strabismus and related ocular alignment deficits. All children whose mothers or fathers had a psychiatric diagnosis of schizophrenia comprised the...

In this chapter, we have reviewed side effects reported for corticotrphins, systemic glucocorticoids, and prostaglandin analogues from January 2020 to June 2021. We used PUBMED, EMBASE International Pharmaceutical Abstracts (IPA) as our search engines. Adrenocorticotropic hormone (ACTH) has found multiple uses but are associated with adverse on cardiac function nervous system. The corticosteroi...

tinct zones, each with different venous drainage. Between these 2 zones, a watershed developed. After the 2 chorioretinal anastomoses matured, blood flow through the venous tributary that bridged the watershed zone— the tributary connecting the inferotemporal branch retinal vein to the central retinal vein—was very slow (Figure 2B). The slow blood flow made that blood vessel susceptible to veno...

A 4-year-old girl was referred to the department of ophthalmology of the Rothschild Hospital, Haifa, because of a blue discoloration of the sclerae from birth, bulging of the eyes which had been first noticed at the age of4 months, and apparent short sight. The child was the product of a normal pregnancy and a normal full-term delivery. The birth weight was 3-6 kg. There had been three episodes...

Abstract Background Xeroderma pigmentosum (XP) is a rare autosomal recessive skin disorder characterized by hyperpigmentation, premature aging, ocular and cutaneous photosensitivity with increased risk of tumors. XP caused mutations in DNA repair genes that protect cells from UV-induced damage. The current study aims to investigate, on clinical genetic basis, Moroccan patients. We explored dire...