Digital human modeling (DHM), as a convenient and cost-effective tool, is increasingly incorporated into product and workplace design. In product design, it is predominantly used for the development of driver-vehicle systems. Most digital human modeling software tools, such as JACK, RAMSIS and DELMIA HUMANBUILDER provide functions to predict posture and positions for drivers with selected anthr...

the kinetics of old corrugated container (occ) soda-oxygen delignification was investigated. three delignification temperatures (145,165 and 175ºc) were applied. the pulping duration was adjusted at 150 minutes and the measurements were conducted at 10 minutes intervals. the pulping consistency, oxygen pressure and active alkali were constant at 10%, 6 bar and 18% naoh respectively in all pulpi...

We previously showed that nordihydroguaiaretic acid (NDGA) and other antioxidants inhibit the resumption of meiosis in oocyte-cumulus complexes (OCC) and denuded oocytes (DO). Because NDGA is well known to be an inhibitor of lipoxygenases (LOX), we assessed whether other LOX inhibitors influence spontaneous germinal vesicle breakdown (GVBD) in OCC and DO. Spontaneous GVBD in rat OCC obtained fr...

The dictionary matching is a task to find all occurrences of pattern strings in a set D (called a dictionary) on a text string T . The Aho-Corasick-automaton (AC-automaton) which is built on D is a fundamental data structure which enables us to solve the dictionary matching problem in O(d log σ) preprocessing time and O(n log σ + occ) matching time, where d is the total length of the patterns i...

Background: In contrast to pharyngo-laryngeal cancer, definitive radiation-chemotherapy of advanced oral cavity cancer (OCC) results in inferior disease control rates. Surgery in combination with radiation +/concomitant chemotherapy is therefore the treatment of choice for squamous cell OCC stages >/=pT1-2pN0-1. Modern intensity modulated radiation techniques (IMRT) allow more conformal dose di...

Automobile crashes are the largest cause of death for pregnant females and the leading cause of traumatic fetal injury mortality in the United States. A previously validated MADYMO computer model of a 30-week pregnant occupant was used in this study to investigate the pregnant occupant response in a severe frontal motor vehicle crash. This study presents simulations of 26 different severe car c...

The primary consumers of building energy are heating, cooling, ventilation, and lighting systems, which maintain occupant comfort, and electronics and appliances that enable occupant functionality. The optimization of building energy is therefore a complex problem highly dependent on unique building and environmental conditions as well as on time dependent operational factors. To provide comput...

Previous results suggest that extracellular dopamine (DA) in the rat cerebral cortex originates from dopaminergic and noradrenergic terminals. To further clarify this issue, dialysate DA, dihydroxyphenylacetic acid (DOPAC) and noradrenaline (NA) were measured both in the medial prefrontal cortex (mPFC) and in the occipital cortex (OCC), with dense and scarce dopaminergic projections, respective...

Developed in the early 1980’s, the flail space model has become the standard method for estimating occupant risk in full-scale crash tests involving roadside safety features. The widespread availability of airbags and increased seat belt usage rates in today’s vehicle fleet, however, raise serious questions regarding the validity of the model. Recent implementation of Event Data Recorder (EDR) ...

OBJECTIVE A 3-phase real-world motor vehicle crash (MVC) reconstruction method was developed to analyze injury variability as a function of precrash occupant position for 2 full-frontal Crash Injury Research and Engineering Network (CIREN) cases. METHOD Phase I: A finite element (FE) simplified vehicle model (SVM) was developed and tuned to mimic the frontal crash characteristics of the CIREN...