197 words) An ERS Research Seminar on “Metabolic alterations in obstructive sleep apnea (OSA)” was jointly organised in October 2009 together with two EU COST Actions (“Cardiovascular Risk in the Obstructive Sleep Apnea Syndrome” Action B26, and “Adipose Tissue and the Metabolic Syndrome” Action BM0602) in order to discuss the interactions between obesity and OSA. Such interactions can be parti...

Purpose In the treatment of obstructive sleep apnea (OSA), there is not yet a convenient tool for deciding whether mandibular advancement oral appliance (OA) adequately adjusted or when to perform post-treatment sleep-testing. We hypothesized that gradual reduction in STOP (snoring, tiredness during daytime, observed apnea, high blood pressure) score, i.e., fewer Yes responses questionnaire, pa...

A 4-yr-old girl has exhibited severe snoring, restless sleep and increasing daytime sleepiness over the last 3 months. The physical examination showed that she was not obese but had kissing tonsils. Polysomnography demonstrated increased apnea-hypopnea index (AHI) of 5.2, and multiple sleep latency tests (MSLT) showed shortened mean sleep latency and one sleep-onset REM period (SOREMP). She was...

background obstructive sleep apnea (osa) is a common sleep disease. it is associated not only with hypertension but also with other cardiac complications. thus, the early detection of cardiac disorders is very useful. objectives we sought to evaluate different echocardiographic parameters. patients and methods this cross-sectional study was done on 55 patients with osa. the patients were divide...

Sleep apnea (AP) is the most commonly known sleeping disorder characterized by pauses of airflow to the lungs and often results in day and night time symptoms such as impaired concentration, depression, memory loss, snoring, nocturnal arousals, sweating and restless sleep. Obstructive Sleep Apnea (OSA), the most common SA, is a result of a collapsed upper respiratory airway, which is majorly un...

 Abstract Bckground: Patients with obstructive sleep apnea (OSA) are at risk of developing the fatty liver as a result of being overweight. Several studies suggest that OSA per se could be a risk factor for liver injury and ischemic hepatitis with OSA. The OSA is an independent risk factor for Insulin resistance. Therefore, we investigated liver enzymes and insulin resistance in patients with O...

Abstract Introduction Adenotonsillectomy (AT) is the most common surgical treatment for pediatric obstructive-sleep-apnea (OSA) with fair effectiveness. There are still controversies about improvement of neurocognitive function after AT. This study investigates changes AT in preschool and school age children OSA, including intelligence attention, explore inconsistent improvements by comparing d...

Two obese patients with sleep apnea syndrome were administered chlormadinone acetate (CMA), a synthetic progesterone, known as a potent respiratory stimulant to augment load compensation response as well as CO2 chemosensitivity. Before CMA administration, both cases showed normal chemosensitivity of hypoxic and hypercapnic ventilatory responses (HVR and HCVR) at daytime, although marked oxygen ...

Sleep-disordered breathing is a common and serious cause of metabolic, cardiovascular, and neurocognitive morbidity in children. The spectrum of obstructive sleep-disordered breathing ranges from habitual snoring to partial or complete airway obstruction, termed obstructive sleep apnea (OSA). Breathing patterns due to airway narrowing are highly variable, including obstructive cycling, increase...

background and objective: sleep-disordered breathing (sdb) is associated with increased morbidity and mortality in patients with heart failure (hf). we assessed the prevalence and the pattern of sdb in hf patients who were candidates for heart transplantation. materials and methods: twenty heart transplantation patients with ventricular ejection-fraction < 25% were recruited consecutively in a ...