Method Participants were 147 discordant sister pairs (total of 297 participants) for EDs. The semi-structured EATATE interview [designed to assess ED symptomatology and obsessive-compulsive personality traits (OCPD)], the Temperament and Character Inventory (TCI-R) and the Oxford Risk Factor Interview (ORFI) were used. DNA was also collected and three candidate genes (5-HT2A, BDNF and 5-HTTLPR)...

The current study quantitatively examined the relation between cognitive inflexibility and obsessive-compulsive personality traits and also examined whether depression and anxiety were mediators of that relation. A total of 56 individuals, ages 18 to 40, participated in the study and were recruited from the undergraduate and graduate student body of The University of Southern Mississippi as wel...

There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice, there are few reports about psychopharmacological treatment for obsessive compulsive symptoms in children with ASD in the literacy. We report a successful treatment ...

BACKGROUND Cognitive models of obsessive-compulsive disorder suggest that changes in obsessive beliefs are a key mechanism of treatments for obsessive-compulsive disorder. Thus, in the present process-outcome study, we tested whether changes in obsessive beliefs during a primarily cognitive behavioral inpatient treatment predicted treatment outcome and whether these changes mediated symptom cha...

This study aimed to investigate the association of obsessive-compulsive symptoms with clinical and neurocognitive features in patients with schizophrenia. This study enrolled 163 people with schizophrenia who were receiving risperidone monotherapy. Comorbid obsessive-compulsive symptoms were assessed using the Yale-Brown Obsessive-Compulsive Scale, and subjects with a score ≥ 10 constituted the...

The predictive value of interpersonal schemas, perfectionism, and thought action-fusion in obsessive-compulsive disorder Objective: Cognitive vulnerability factors are central in the etiology of obsessive-compulsive disorder. Nosological classifications among symptom clusters have been developed to enable the understanding of possible mechanisms underlying obsessive compulsive symptoms. Previou...

Obsessive-compulsive disorder is a common chronic neuropsychiatric illness. Estimates of the lifetime prevalence rate of obsessive-compulsive disorder will vary depending on the methods used to gather the epidemiological data and the diagnostic criteria used to define obsessive-compulsive disorder. Estimates of the lifetime prevalence of obsessive-compulsive disorder have been reported to be to...