Repeated surveys have shown that the magnitude of nutritional anaemia is of public health concern in India. Though reduced intake of iron is a major aetiological factor, low intake or an imbalance in the consumption of other haematopoietic nutrients, their utilization; increased nutrient loss and/or demand also contribute to nutritional anaemia. In India, cereals and millets form the bulk of th...

Two pharmacokinetic methods are used primarily to assess systematic bioavailability of orally dosed water-soluble compounds in vivo, but there have been no direct comparisons of the estimates obtained. The "area under the curve" (AUC) method employs a single oral dose of probe compound(s) followed by multiple blood sampling to obtain plasma concentration time curves. Separate injection of probe...

Methionine is an essential amino acid for animals and is typically considered one of the first limiting amino acids in animal feed formulations. Methionine deficiency or excess in animal diets can lead to sub-optimal animal performance and increased environmental pollution, which necessitates its accurate quantification and proper dosage in animal rations. Animal bioassays are the current indus...

Biofortification of commonly eaten staple food crops with essential mineral micronutrients is a potential sustainable solution to global micronutrient malnutrition. Because phytic acid (PA; 1,2,3,4,5,6-hexakis myo-inositol) reduces mineral micronutrient bioavailability, reduction of PA levels could increase the bioavailability of biofortified iron (Fe), zinc (Zn), calcium (Ca), and magnesium (M...

Montmorillonite has been widely used in remediation of toxic metals. However, for the safety soil ecosystem, impact this technology on microorganisms is still unclear. Here, influence nano-montmorillonite immobilization, accumulation cadmium, and microbial activity a soil–plant system was investigated. The results revealed that treatments reduced cadmium bioavailability uptake by oilseed rape. ...

present study determines not only the total amounts of metals (cr, cu and pb) in superficial agricultural soil of sistan area in eastern iran, but also the chemical partitioning of these elements in seven statistically selected cases. the analysis was run for local soil, soil treated by non-contaminated organic, compost and chemical fertilizers as well as soil treated by metal-contaminated fer...

the supersaturatable self-microemulsifying drug delivery system (s-smedds) represents a new thermodynamically stable formulation approach wherein it is designed to contain a reduced amount of surfactant and a water-soluble polymer (precipitation inhibitor or supersaturated promoter) to prevent precipitation of the drug by generating and maintaining a supersaturated state in-vivo. the supersatur...

Electrocoagulation is a promising technology to harvest and concentrate microalgae while saving costs on secondary dewatering steps. However, the sacrificial electrodes release salts that impact media harvested biomass. This study evaluated effects of Fe, Zn, Mg Nannochloropsis oceanica harvesting elementary composition biomass supernatants. Moreover, plant bioavailability electrocoagulation mi...

the bioavailability of two dipyridamol tablet formulations of (dipyridamole from tolidaru and persantin from boehringer) was compared in 14 healthy male volunteers who received a single dose of 25 mg of the test (t) and the reference (r) products in a randomized balanced 2-way crossover design. plasma samples were obtained over a 16 h interval and dipyridamole concentrations determined by hplc ...

background: the aim of this study was to determine bioavailability heavy metal concentrations of cu, cd, cr, co and zn and health risk assessment in different types of klang district, selangor (malaysia) urban surface soil using in physiologically based extraction test in vitro human digestion model. methods: a total of 76 urban surface soil was sampled based on seven different types of land us...