The seagull terms for the electric polarizability of the nucleon are shown to vanish indeed, if one introduces fluctuations around the Skyrmion configuration, and after all the origin of the electric polarizability cannot be attributed to the seagull terms in the Skyrme model. E-mail address [email protected] E-mail address ueharam@cc. saga-u.ac.jp 1

Eccentric millisecond pulsars (eMSPs) with white dwarf companions exhibit orbital eccentricities orders of magnitude larger than predicted by turbulent convection in the dwarfs' red giant progenitors. The periods eMSPs cluster around $P=20-30$ d, remarkably close to convective eddy turnover time $t_{\rm eddy}$. We propose that anomalously large are resonantly driven flows somehow made coherent ...

A large-scale outbreak of food poisoning caused by consumption of skimmed milk powder contaminated with staphylococcal enterotoxin A (SEA) occurred in Japan. No viable Staphylococcus aureus was detected in the skimmed milk powder, however, sea and nuc genes of S. aureus were detected in it by PCR. The number of S. aureus in skimmed milk powder was estimated by quantitative real-time PCR.

Treatment options for chronic hepatitis B (CHB) are pegylated interferon (Peg-IFN) in minimal-mild liver fibrosis and nucleot(s)ide analogues (NUC) in more advanced disease. Since little is known about their use in daily clinical practice, we conducted a multicentre prospective study to investigate treatment regimens applied to naïve CHB patients in real life. HBV-RER is an observational multic...

INTRODUCTION Circulating nucleosomes released from apoptotic cells are important in the pathogenesis of systemic lupus erythematosus (SLE). Both nucleosomes and anti-nucleosome antibodies are deposited in inflamed tissues in patients with SLE. Active inflammation promotes nitration of tyrosine residues on serum proteins. Our hypothesis was that levels of nitrated nucleosomes would be elevated i...

To get insight into the regulation of human interleukin-12 (IL-12) synthesis, we determined the chromatin organization of the IL-12(p35) promoter region. First, we determined positioning of nucleosomes within the IL-12(p35) promoter using the indirect end-labeling technique in the THP-1 monocytic cell line. On stimulation with bacterial lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma),...

Following human immunodeficiency virus type 1 (HIV-1) integration into the host cell's genome, the 5' long terminal repeat (LTR) is packaged into a highly specific chromatin structure comprised of an array of nucleosomes positioned with respect to important DNA sequence elements that regulate the transcriptional activity of the provirus. While several host cell factors have been shown to be imp...

[1] We have studied the temporal and spectral variations of anomalous oxygen nuclei at the Voyager 1 (V1) and 2 (V2) spacecraft in the outer heliosphere from 1990 to the present time in 2006 when V1 is now beyond the heliospheric termination shock. During this time period, the intensities increased from their lowest values in 1990–1991 up to a maximum in 1998–1999 and then decreased rapidly in ...

UNLABELLED Neisseria gonorrhoeae is naturally competent for transformation. The first step of the transformation process is the uptake of DNA from the environment into the cell. This transport step is driven by a powerful molecular machine. Here, we addressed the question whether this machine imports single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) at similar rates. The fluorescence ...