Ditte Caroline Andersen,1,2,* Charlotte Harken Jensen,1 and Søren Paludan Sheikh1,3 1Laboratory of Molecular and Cellular Cardiology, Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, 5000 Odense C, Denmark 2Clinical Institute/University of Southern Denmark, 5000 Odense C, Denmark 3Institute of Molecular Medicine/University of Southern Denmark, 5000 Odense C, Den...

Canul-Chay et al. [1] have conducted the segregation experiment of binary granular mixtures in a bed and subjected the bed to vibration. They report that the reverse Brazil-Nut phenomenon (RBNP) was never observed in their experiments and thus conclude that such does not exist. However, we have clearly demonstrated in [2] by Molecular Dynamics simulations that the reverse Brazil-Nut problem not...

The serpin (serine proteinase inhibitor) superfamily includes antithrombin, α1-antitrypsin and PAI-1, which control the coagulation, inflammation and fibrinolytic pathways, respectively. Serpins have a unique method of inhibition that involves a conformational change of the protein (Huntington et al., 2000). This transition is essential for the mechanism of serpin inhibition but it renders serp...

Soon after birth, neurogenesis is completed within most brain regions. Notable exceptions are found within germinative areas that persist in restricted CNS regions into adulthood. These include the dentate gyrus of the hippocampus and, particularly, an extensive forebrain periventricular region (PVR) (for reviews, see Peretto et al., 1999; Temple and Alvarez-Buylla, 1999; Gage, 2000; Alvarez-Bu...

In Response to Fakruddin et al. dicted to result in substitutions of amino acids at the and Apostolou et al. corresponding positions in the protein sequence. In each of these cases, individual tumor DNA samples possessed the same sequence as that of the corresponding cell line. We agree with many of the above findings, including To determine if the divergent sequences represented the frequency ...

Tetrazolium dyes have often been used as electron acceptors in measurements of cell proliferation rates (Berridge and Tan, 1993; Ishiyama, et al., 1993; Berridge, et al., 1996), in histochemical procedures (Zamudio, et al., 1969; May, et al., 1995b; Demehin, et al., 2001), and for assaying redox enzymes (Berridge and Tan, 1993; Mittler and Zilinskas, 1993; Debnam and Shearer, 1997; Ye, et al., ...

Active joints Hypermobile robots: • Koryu-I and Koryu-II (Hirose, 1993) • Snake 2 (Klaassen and Paap, 1999) • Soryu (Takayama and Hirose, 2000) • Millibot Train (Brown et al., 2002) • Moira (Osuka & Kitajima, 2003) • Pipeline Explorer (Schempf et al., 2003) • Omnis family (Granosik et al., 2005) • MAKRO plus (Streich & Adria, 2004) • KOHGA (Kamegawa et al., 2004) • JL-I (Zhang et al., 2006) • W...

Following the works of Velazquez et al. (1999), Jo-Seung et al. (2000), Wang et al. (2001), Danscher et al. (2001) and the criteria of Zinc-containing neurons established by Frederickson et al.(2000), we have found the presence and localisation of Zinc in the neurons of the dorsal root ganglia of Wistar rat, by using Timm's thecnique and by studying the autoradiographic uptake of 65Zn. The agre...

Nightlight Christian Adoptions [3] et al. v. Thompson et al. was a lawsuit filed in the United States District Court for the District of Columbia on 8 March 2001. The suit was filed because Nightlight Christian Adoptions [3], a frozen embryo [4] adoption agency, felt that the Guidelines for Research Using Human Pluripotent Stem Cells [5] published by the National Institutes for Health were unla...

In the last issue, I presented a piece that called into question some of the techniques reported in two papers in high-profile journals that purported to provide statistical evidence for the linguistic status of some ancient symbol systems (Sproat 2010a). Not surprisingly the authors of those two papers took issue with a number of my claims, and have requested the opportunity to respond. The tw...