[1] Soil NOx emission from agricultural regions in the western United States has been investigated using satellite observations of NO2 from the SCIAMACHY instrument. We show that the SCIAMACHY observations over a 2 million hectare agricultural region in Montana capture the short intense NOx pulses following fertilizer application and subsequent precipitation and we demonstrate that these variat...

Sustained upregulation of inducible nitric oxide (NO) synthase in the liver after endotoxin [lipopolysaccharide (LPS)] challenge may result in hepatocellular injury. We hypothesized that administration of a NO scavenger, NOX, may attenuate LPS-induced hepatocellular injury. Sprague-Dawley rats received NOX or saline via subcutaneous osmotic pumps, followed 18 h later by LPS challenge. Hepatocel...

NADPH-oxidase (NOX) mediated superoxide originally found on leukocytes, but now recognized in several types of cells in the brain. It has been shown to play an important role in the progression of stroke and related cerebrovascular disease. NOX is a multisubunit complex consisting of 2 membrane-associated and 4 cytosolic subunits. NOX activation occurs when cytosolic subunits translocate to the...

Prostate cancer (PCa) is the leading malignancy among men. Importantly, this disease is mostly diagnosed at early stages offering a unique chemoprevention opportunity. Therefore, there is an urgent need to identify and target signaling molecules with higher expression/activity in prostate tumors and play critical role in PCa growth and progression. Here we report that NADPH oxidase (NOX) expres...

Thunderstorm anvils were studied during the Deep Convective Clouds and Chemistry experiment (DC3), using in situ measurements and observations of ice particles and NOx together with radar and Lightning Mapping Array measurements. A characteristic ice particle and NOx signature was found in the anvils from three storms, each containing high lightning flash rates in the storm core prior to anvil ...

NADPH oxidases (NOXs) constitute a family of enzymes generating reactive oxygen species (ROS) and are increasingly recognized as interesting drug targets. Here we investigated the effects of 10 phenothiazine compounds on NOX activity using an extensive panel of assays to measure production of ROS (Amplex red, WST-1, MCLA) and oxygen consumption. Striking differences between highly similar pheno...

Several experimental studies have indicated that nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) exert detrimental effects on ischemic brain tissue; Nox-knockout mice generally exhibit resistance to damage due to experimental stroke following middle cerebral artery occlusion (MCAO). Furthermore, our previous MCAO study indicated that infarct size and blood-brain barrier break...

In order to investigate the role of erythropoietin (EPO) in the hippocampus, we studied the effect of EPO on nitric oxide (NO) production in the rat hippocampus using brain microdialysis. The dialysis probe was stereotaxically inserted into the rat hippocampus 24 h before the dialysis experiment. The perfusion fluid (Krebs-HEPES buffer, pH 7.4) was collected at 15-min intervals under freely mov...

In this study, we build a new thermal power sector NOx emissions prediction model of tandem gray BP neural network. Firstly we use 1994-2010 years NOx emissions data to establish three gray prediction models: GM (1,1), WPGM (1,1) and pGM (1,1); Secondly, by comparison, we select the best prediction model pGM (1,1) and at the same time take NOx emissions factors as the BP neural network input, 1...

The nitrogen oxides (NOx) are prominent and harmful pollutants in the exhaust of diesel engines. The reduction of NOx to harmless products using catalysts is proved to be a remedy. The present study attempts to reduce NOx emissions in the exhaust of low heat rejection (LHR) diesel engine by catalytic reduction, using lanthanum ion exchanged zeolite (catalyst-A) and urea infused lanthanum ion ex...