نتایج جستجو برای: novelty p3

تعداد نتایج: 30238  

برش نمونة سازند پابده (پالئوسن فوقانی - الیگوسن زیرین) در تاقدیس (کوه) گورپی، زاگرس و خوزستان قرار گرفته است و ازنظر سنگ‌شناختی شامل تناوب مارن‌های ارغوانی و سفید، آهک مارنی و آهک نازک تا ضخیم لایة غنی از فرامینیفر‌های پلانکتونیک است. باتوجه‌به نبود شواهد فرسایش قاره‌ای یا خروج حوضه از آب، مرز پایینی این سازند با سازند گورپی پیوسته است و مرز بالایی آن با سازند آسماری پیوسته و تدریجی است. مطالعا...

Journal: :journal of basic and clinical pathophysiology 2015
samira geravand manizheh karami mohammadreza jalali nadoushan

background and objective: identifying the details of the injurious effects of alcohol seems to be decisive in nowadays with growing abuse of the substance. this study mainly aimed to assess the adverse effects of ethanol on the recalling of information in the wistar rats. materials and methods: male wistar rats (pasteur institute of iran) were evaluated using the novelty seeking behavior based ...

2018
Chun Liu Sanghamitra Deb Vinicius S. Ferreira Eric Xu Tobias Baumgart

Phosphatidylinositides play important roles in cellular signaling and migration. Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an important phosphatidylinositide because it acts as a secondary messenger to trigger cell movement and proliferation. A high level of PI(3,4,5)P3 at the plasma membrane is known to contribute to tumorigenesis. One key enzyme that regulates PI(3,4,5)P3 leve...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Martin Drucker Remy Froissart Eugénie Hébrard Marilyne Uzest Marc Ravallec Pascal Espérandieu Jean-Claude Mani Martine Pugnière Francoise Roquet Alberto Fereres Stéphane Blanc

Interactions between Cauliflower mosaic virus (CaMV) and its aphid vector are regulated by the viral protein P2, which binds to the aphid stylets, and protein P3, which bridges P2 and virions. By using baculovirus expression of P2 and P3, electron microscopy, surface plasmon resonance, affinity chromatography, and transmission assays, we demonstrate that P3 must be previously bound to virions i...

2004
Emilia I. Barakova

In analogy to animal research, where behavioral and internal neural dynamics are simultaneously analysed, this paper suggests a method for emergent behaviors arising in interaction with the underlying neural mechanism. This way an attempt to go beyond the indeterministic nature of the emergent behaviors of robots is made. The neural dynamics is represented as an interaction of memories of exper...

2015
Daniel Kitterer Joerg Latus Christoph Pöhlmann M. Dominik Alscher Martin Kimmel A Al-Ahmad

OBJECTIVES Peritonitis is one of the most important causes of treatment failure in peritoneal dialysis (PD) patients. This study describes changes in characteristics of causative organisms in PD-related peritonitis and antimicrobial susceptibility. METHODS In this single center study we analyzed retrospective 487 susceptibility profiles of the peritoneal fluid cultures of 351 adult patients w...

Journal: :FEBS letters 1991
M S Islam T Nilsson P Rorsman P O Berggren

Electropermeabilised insulin-secreting RINm5F cells sequestered Ca2+, resulting in a steady-state level of the ambient free Ca2+ concentration corresponding to 723 +/- 127 nM (mean +/- SEM, n = 10), as monitored by a Ca(2+)-selective minielectrode. Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) promoted a rapid and pronounced release of Ca2+. This Ca2+ was resequestered and a new steady-state Ca2+...

Journal: :Journal of Alzheimer's disease : JAD 2012
Kenji Kamogawa Katsuhiko Kohara Yasuharu Tabara Rie Takita Tetsuro Miki Tomoko Konno Saori Hata Toshiharu Suzuki

Alcadeins (Alcs) constitute a family of neuronal type I membrane proteins (α, β, γ) that share identical localization and function to the amyloid-β protein precursor (AβPP) in the brain. Alcs are proteolyzed in neurons through successive cleavages via secretases, resulting in non-aggregative p3-Alc, where p3 corresponds to the AβPP-fragment. We found p3-Alcα detected in human plasma reflected t...

2017
Shaohui Tang Yanfang Chen Shufen Feng Tingzhuang Yi Xuyou Liu Qiang Li Zhilong Liu Cuiping Zhu Jianjun Hu Xi Yu Min Wang Guoli Cao Hui Tang Caiqun Bie Feng Ma Huijun Tang Gang Du Jianwei Huang

The human insulin-like growth factor-II (IGF-II) gene transcribes four mRNAs (P1 mRNA-P4 mRNA), and P3 mRNA overexpression contributes to hepatocarcinogenesis. IGF-II-derived miR-483-5p is implicated in the development of cancers. Here, we investigated the involvement of miR-483-5p in P3 mRNA overexpression regulation and its role in hepatocellular carcinoma. Our results showed that miR-483-5p ...

2014
Mauro Marchetti Konstantinos Priftis

A quarter of century ago, Farwell and Donchin (1988) described their mental prosthesis for "talking off the top of your head." This innovative communication system, later named P3-speller, has been the most investigated and tested brain-computer interface (BCI) system, to date. A main goal of the research on P3-spellers was the development of an effective assistive device for patients with seve...

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