نتایج جستجو برای: non canonical function

تعداد نتایج: 2415887  

2006
Lynne H. Walling LYNNE H. WALLING

We apply the Hecke operators T (p) and T̃j(p 2) (1 ≤ j ≤ n, p prime) to a degree n theta series attached to a rank 2k Z-lattice L, n ≤ k, equipped with a positive definite quadratic form in the case that L/pL is hyperbolic. We show that the image of the theta series under these Hecke operators can be realized as a sum of theta series attached to certain closely related lattices, thereby generali...

2015
Valentina Turinetto Claudia Giachino

In the last decade, many papers highlighted that the histone variant H2AX and its phosphorylation on Ser 139 (γH2AX) cannot be simply considered a specific DNA double-strand-break (DSB) marker with a role restricted to the DNA damage response, but rather as a 'protagonist' in different scenarios. This review will present and discuss an up-to-date view regarding the 'non-canonical' H2AX roles, f...

2014
Daniel P. S. Osborn Rosa Maria Roccasecca Fiona McMurray Victor Hernandez-Hernandez Sriparna Mukherjee Inês Barroso Derek Stemple Roger Cox Philip L. Beales Sonia Christou-Savina

Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an increased risk of obesity. Overexpression of FTO correlates with increased food intake and obesity, whilst loss-of-function results in lethality and severe developmental defects. Despite intense scientific discussions around the role of FTO in energy metabolism, the function of FT...

Journal: :Development 2003
Bisei Ohkawara Takamasa S Yamamoto Masazumi Tada Naoto Ueno

Coordinated morphogenetic cell movements during gastrulation are crucial for establishing embryonic axes in animals. Most recently, the non-canonical Wnt signaling cascade (PCP pathway) has been shown to regulate convergent extension movements in Xenopus and zebrafish. Heparan sulfate proteoglycans (HSPGs) are known as modulators of intercellular signaling, and are required for gastrulation mov...

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه ملی مهندسی ژنتیک وزیست فناوری 1390

آستروسیت ها که عمده ترین سلول های غیر نورونی در مغز می باشند، در پشتیبانی و نگهداری نورون ها نقش دارند. دخالت مسیر پیام رسانی pi3k/akt در ترشح فاکتور محافظ عصبی tgf-? در آستروسیت ها، القا شده با استرادیول، گزارش شده است. در این پایان نامه احتمال شرکت مسیر پیام رسانی canonical wnt در تولید فاکتورهایی از خانواده ی tgf-? نظیر tgf-?و bmp-4 توسط آستروسیت ها بررسی گردید. آستروسیت های جداشده از کورتکس...

Journal: :International journal of oncology 2008
Kwesi Teye Kengo Okamoto Yuji Tanaka Toshiyuki Umata Masaaki Ohnuma Masaaki Moroi Hiroshi Kimura Makoto Tsuneoka

Transcription factor binding sites are short DNA sequences that interact with transcription factors and the proper control of gene expression appears to require the mechanisms including the regulation through the genome context around the transcription factor binding sites. The MYC proteins are central regulators of cell growth. Many genes have been reported to be regulated by MYC through E-box...

A. Ghaani Farashahi

Finite affine groups are given by groups of translations and di- lations on finite cyclic groups. For cyclic groups of prime order we develop a time-scale (wavelet) analysis and show that for a large class of non-zero window signals/vectors, the generated full cyclic wavelet system constitutes a frame whose canonical dual is a cyclic wavelet frame.

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