The global descriptors of chemical activity: ionization potential IP, electron affinity EA, ?, absolute electronegativity ?, molecular hardness ? and softness S, electrophilicity index ? for cyanides X(CN)k with X=H, Na, K, Ag, Cu, Ca, Hg, Cd, Zn in the gas phase water medium have been determined by taking advantage quantum-chemical computations. To this aim, HOMO LUMO energy levels were calcul...

stachys lavandulifolia ( s. lavandulifolia ) is a plant that has been widely used as an herbal medicine in iran. unfortunately, despite the prevalent medicinal uses of the plant, there are no reports on the possible toxic effects of s. lavandulifolia . in the present study the potential toxicity of s. lavandulifolia after acute and sub-chronic administration in rats was evaluated. rats were ora...

in iranian folk medicine, especially in west of the country, the aromatic water of rheum ribes has been used for several purposes such as fever reduction.  despite the widespread use of this plant as food or as a medicinal plant, there is still lack of information on its toxicity profile.                                                                in the present study we aimed to evaluate th...

Sansevieria trifasciata is one of popular ornamental plants which also believed possessing therapeutic effects due to their phytochemical constituents. Secondary metabolites can be toxic other organisms; therefore, toxicity studies must carried out investigate adverse prior further exploration as potent candidates medicinal plants. This research aimed evaluate and safety consuming chloroform ex...

Elevated human exposure to metals and metalloids (metal(loid)s) may lead acute sickness pose a severe threat health. The body is exposed metal(loid)s principally through food, water, supplements, (occasionally) air. There are inherent background levels of many in regional soils as consequence geological sources. Baseline coupled with anthropogenic sources such application biosolids increased ce...

Obesity is one of the pandemic chronic diseases commonly associated with health disorders such as heart attack, high blood pressure, diabetes or even cancer. Among the current natural products for obesity and weight control, Garcinia or more specifically hydroxycitric acid (HCA) extracted from Garcinia has been widely used. The evaluation of the potential toxicity of weight control supplement i...

Phikud Navakot (PN) is commonly used in Thai traditional medicine for alleviation of cardiovascular and cerebrovascular symptoms; however little is known about the chronic toxicity effects of the extracts from the herbs in PN. Repeated extraction doses of 10, 100, and 1,000 mg/kg/day were randomly administered to both male and female Sprague Dawley rats for 12 months. Histopathological study re...

ETHNOPHARMACOLOGICAL RELEVANCE Maydis stigma (corn silk) has a long history of use as a traditional herbal medicine or functional food in China and many other countries and has been listed in the Chinese Pharmacopea. However, little data about its potential toxicity is available. AIM OF THE STUDY In this study, we evaluated the subchronic toxicity and genotoxicity of the flavonoid-rich extrac...

OBJECTIVES This paper presents toxic effects of 2-MN in laboratory animals under conditions of 4-week inhalation exposure to 2-methylnaphthalene (2-MN) vapors. MATERIALS AND METHODS Male Wistar rats were exposed to 2-MN vapors at a nominal concentration of 0, 2, 10 or 50 mg/m(3) in dynamic inhalation chambers for 4 weeks (6 h/day, 5 days/week). After 4 weeks of inhalation exposure the animals...