use of different pesticides in the agriculture sector, in order to boost crop yield within a short time period and low labor, has been tremendously increased since the last decade. pesticide use has elevated crop yield but has produced a number of pronounced problems regarding environmental and health safety. the continuously deteriorating toxicological effects of these pesticides are not only ...

background: occupational and environmental exposures mostly represent complex mixture of genotoxic agents, however there is a wide variation in the specificity of biomarkers. exploration of correlations among biomarkers contributes to the further progress of molecular cancer epidemiology and to the selection of the optimal biomarkers for the investigation of human exposure to carcinogens. the a...

the purpose of this study was to survey impacts of drought on socio-economic conditions of guilan paddy farmers. besides recognizing these impacts, it ranked them according to the viewpoint of the paddy farmers. it was of the descriptive- correlation type. questionnaire was the main tool of this study. to determine the validity of questionnaire used of comments of panel experts and reliability ...

an improved model of mud dispersion has been introduced in this work. the advantages of this model consist of a new analytical correlation for dispersivity by using resistivity log data and using a new aspect of capacitance dispersion model. mathematical formulations were expressed, solved by numerical model taking advantage of actual log and formation data. achieved results yielded reasonable ...

Background: Lymphocytes of Fanconi anemia (FA) show an increased sensitivity to the alkylating agents such as mitomycin C (MMC), but their responses to gamma-irradiation is controversial. The extent of DNA damage in leukocytes of FA patients following irradiation and MMC treatment was studied at cellular and single chromosome level. Methods: DNA damage induced by gamma-rays and MMC was measure...

BACKGROUND Tumour necrosis factor alpha (TNF-alpha) is involved in non-steroidal anti-inflammatory drug induced gastropathy. Nitric oxide (NO) is a mediator of gastrointestinal mucosal defence but, paradoxically, it also contributes to mucosal damage. AIMS We optimised the C57BL/6 mouse model of indomethacin induced gastropathy to evaluate the role of TNF-alpha and inducible nitric oxide synt...

In previous reports from this study, measurements of pulmonary inflammation, bronchoalveolar lavage cell cytokine production and nuclear factor-kappa B activation, cytotoxic damage, and fibrosis were detailed. In this study, we investigated the temporal relationship between silica inhalation, nitric oxide (NO), and reactive oxygen species (ROS) production, and damage mediated by these radicals ...