SCOPE In order to validate the in vivo function of putatively healthy molecules in foods, human intervention studies are required. As the subject's compliance concerning intake or abstinence of a given food is considered mandatory to be monitored by biomarkers, the objective was to identify analytical markers for coffee consumption. METHODS AND RESULTS Urine samples collected from coffee drin...

The photoisomerization dynamics of N-methyl-2-pyridone (NMP) dissolved in CH3CN have been interrogated by time-resolved electronic and vibrational absorption spectroscopy. Irradiation at two different wavelengths (330 or 267 nm) prepares NMP(S1) molecules with very different levels of vibrational excitation, which rapidly relax to low vibrational levels of the S1 state. Internal conversion with...

Hybrid materials formed by the combination of inorganic components with organic polymers have emerged as a rapidly expanding and internationally competitive field research in polymer science. These show great promise many important applications where control surface properties, well structure interfacial interactions between two primary components, are determinant. In this paper, we present rev...

pH-Responsive block copolymers, having two segments with functionalities of differing pK(a), were prepared by NMP, providing a "green" route to the assembly of core-shell functionalizable nanostructures.

Existe vaguedad respecto de la evaluación los servidores públicos con nombramiento provisional en el sistema empleo público vigente Colombia, debido a que criterios legales al son ambiguos. Esta opacidad ha generado división judiciales, así como entes regulación del público. Este artículo argumenta tal genera incertidumbre entre las personas nombradas provisionalidad, funcionarios tienen funció...

Membranes were prepared from a castmg solution of a water-soluble polymer, poly (vmyl pyrrohdone) (PVP), and a membrane forming polymer, poly (ether sulfone), m l-methyl-2-pyrrohdone (NMP) as solvent by immersing them m mixtures of water and NMP It was found that the addltlon of PVP to the ternary system suppresses the formatlon of macrovolds m the sub-layer, while the ultraflltratlon-type top-...

CTLs were generated in vitro from two healthy donors and one melanoma patient by stimulation of CD8+ T cells with autologous dendritic cells pulsed with natural melanoma peptides (NMPs), obtained by acid treatment of HLA-matched melanoma cells. CTLs showed MHC class I-restricted melanoma-specific cytolytic activity. Importantly, CTLs from the patient, induced with NMPs obtained from an allogene...