Optical cavity enhancement is a highly desirable process to make sensitive direct-absorption spectroscopic measurements of unknown substances, such as explosives, illicit material, or other species of interest. This paper reports advancements in the development of real-time cavity ringdown spectroscopy over a wide-bandwidth, with the aim to make headspace measurements of molecules at trace leve...

Thionitrosyl Complexes, Nit rosy 1 Chromium Complexes A nitromethane solution of NS+PFe-, obtained in situ from N3S3CI3 and AgPF6 (1:3), reacts with benzene tricarbonyl chromium in acetonitrile solution to give the thionitrosylcontaining salt [Cr(NS)(NC-Me)s](PF6)2 (1)In the presence of Zerf-butyl isocyanide and Zn powder, 1 is reduced to [Cr(NS)(CN-CMe3)s]PF6 (3), while subsequent oxidation of...

We report the mechanism of asymmetric nitroaldol (Henry) reaction catalyzed by a dinuclear Zn complex using density functional theory. The experimentally proposed catalytic cycle is validated, in which the first step is the deprotonation of nitromethane by the ethyl anion of the catalyst, subsequently a C-C bond formation step, and then the protonation of the resulting alkoxide. Three mechanist...

In situ generated azomethines from readily available precursors react with nitromethane in the presence of 120 mol % of CsOH.H2O and 12 mol % of quinine- and cinchonidine-derived quaternary ammonium chlorides to provide the corresponding aza-Henry adducts in good yields and very high selectivities. It represents the first general enantioselective aza-Henry method for azomethines derived from en...

g -Aminobutiric acid (GABA), the major inhibitory neurotransmitter in the central nervous system has two major receptor subtypes (GABAA and GABAB). GABAB receptors are activated by the antispastic and muscle relaxant agent, Baclofen, which is a lipophilic derivative of GABA. Since 1962 several strategies have been reported for the synthesis of baclofen.In this study an approach has been made to...

The density and viscosity values at T= (293.15 to 323.15) K for binary mixtures of nitromethane with 2-propanol, 2-butanol and 2-pentanol were measured over the entire composition range. From the experimental data, excess molar volumes, thermal expansion coefficients, excess thermal expansions, partial molar volumes at infinite dilution and deviations in viscosity were calculated. The results w...