The source of irregularity in El Niño, the large interannual climate variation of the Pacific ocean-atmosphere system, has remained elusive. Results from an El Niño model exhibit transition to chaos through a series of frequency-locked steps created by nonlinear resonance with the Earth's annual cycle. The overlapping of these resonances leads to the chaotic behavior. This transition scenario e...

High resolution pollen analysis of mid- to late-Holocene peat deposits from southwest Florida reveals a stepwise increase in wetland vegetation that points to an increased precipitation-driven fresh water flow during the past 5,000 years. The tight coupling between winter precipitation patterns in Florida and the strength of the El Niño-Southern Oscillation (ENSO) strongly suggests that the pal...

MRX34, a microRNA (miRNA)-based therapy for cancer, has recently entered clinical trials as the first clinical candidate in its class. It is a liposomal nanoparticle loaded with a synthetic mimic of the tumor suppressor miRNA miR-34a as the active pharmaceutical ingredient. To understand the pharmacokinetic properties of the drug and to rationalize an optimal dosing regimen in the clinic, a met...

Abstract El Nino is one of the natural phenomena that have a significant influence on weather, causing longer dry season in several regions Indonesia, which city Lampung. One way to anticipate long drought predict rainfall, by looking at intensity rain. This paper proposes rainfall prediction using recurrent neural network. Weather variables used include air humidity, wind speed obtained from B...

A generalized-ensemble technique, multicanonical sampling, is used to study the folding of a 34-residue human parathyroid hormone fragment. An all-atom model of the peptide is employed and the protein-solvent interactions are approximated by an implicit solvent. Our results demonstrate that generalized-ensemble simulations are well suited to sample low-energy structures of such large polypeptid...

Ongoing cti sruption of ancient , varnished desert pave ment surfaces ncar Death Valley Nat ional Park is inferred to be the result of unusually intense animal foraging activity. lncreased levels of biotllrbation are associated with enhanced vegetation growth stimulated by recen t EI Nino precipitation. The occurrence of abundant, recen tly overturned, varnished clasts suggests that the pavemen...

In the crystal structure of the centrosymmetric binuclear title complex, [Ni(2)(C(12)H(8)N(2)O(2)S)(2)(CH(3)OH)(4)], there are inter-molecular O-H⋯O, O-H⋯N and O-H⋯S hydrogen bonds. These help to stabilize the structure and link the mol-ecules, forming a three-dimensional network structure. The Ni(2+) cation exists in a slightly distorted octahedral NiNO(5) coordination environment. The thio-ph...

We performed electron spin resonance (ESR) measurements on two kinds of nickel chain compounds doped with nonmagnetic Zn2+ ions, Ni(333-tet)( -NO2)(ClO4) (333-tet=bis-(3-aminopropyl)-1,3-propanediamine) abbreviated as NTENP and Ni(1,3-pn)2( -NO2)(ClO4) (1,3-pn=1,3-propanediamine) abbreviated as NINO which are regarded as a spin (S) one Heisenberg antiferromagnetic bond alternating chain and a u...