1. The beta-adrenoreceptor-blocking effects of pindolol were compared with those of propranolol and a placebo in a double-blind cross-over trial involving nine hypertensive African patients. 2. Heart rate, systolic blood pressure and diastolic blood pressure were measured at rest and immediately after exercise before and at intervals up to 6 h after oral administration of the drugs. In addition...

The reflex control of pulse interval during erect bicycle exercise was studied in nine normal subjects aged 18 to 28, breathing an oxygen-rich mixture. Rises in the directly measured arterial pressure were produced by intravenous injections of phenylephrine, and systolic pressure was correlated with the following pulse interval. The slope of the systolic pressure-pulse interval relation was use...

Thirteen patients with Prinzmetal's variant angina performed treadmill exercise tests in the early morning and in the afternoon of the same day. The attacks with ST elevation were induced repeatedly in all 13 patients in the early morning, but in only two patients in the afternoon. Propranolol did not suppress the exercise-induced attacks in all 13 patients. Diltiazem suppressed the attacks in ...

The purpose of the current study was to examine whether the effects of social support on physical exercise in older adults depend on individual perceptions of self-efficacy. Three hundred nine older German adults (age 65-85) were assessed at 3 points in time (3 months apart). In hierarchical-regression analyses, support received from friends and exercise self-efficacy were specified as predicto...

Directly influenced by Colin Rowe’s essay “Mathematics of the Ideal Villa” (1947) and Warburgian art historical tradition, John Hejduk’s nine-square grid studio exercise had an ambiguous relation to instrumentality architectural history. When was copied in many architecture schools around world as a first-year project, initiating novice student realm composition, pedagogical interpretation its ...

Differences in cardiovascular function between sexes have been documented at rest and maximal exercise. The purpose of this study was to examine the sex differences in cardiovascular function during submaximal constant-load exercise, which is not well understood. Thirty-one male and 33 female subjects completed nine minutes moderate and nine minutes vigorous intensity submaximal exercise (40 an...

BACKGROUND Low physical activity has been shown to be one of the most common components of frailty, and interventions have been considered to prevent or reverse this syndrome. The purpose of this systematic review of randomized, controlled trials is to examine the exercise interventions to manage frailty in older people. METHODS The PubMed, Web of Science, and Cochrane Central Register of Con...

Peak expiratory flow (PEF) and plasma concentrations of platelet factor 4 and beta thromboglobulin were measured before and after exercise in nine asthmatic patients and 12 non-asthmatic volunteers. Exercise was preceded by administration in random order of either placebo, salbutamol 200 micrograms, or sodium cromoglycate 2 mg from a pressurised inhaler. In control subjects there were minimal c...

The objective of this exercise is to demonstrate how a steady state gain matrix, K can be calculated from a linearized state space dynamic process model. The approach used has been published by Arkun and Downs [1], and it is aimed at handling cases where integrating elements, e.g. liquid levels, are present. The dynamic approach is applied to the Tennessee Eastman process, and the relative gain...