BACKGROUND Information on predictors of quitting behavior among construction site tobacco users is scarce in India. Hence, this study was conducted to assess the intention of tobacco users toward quitting and its predictors with reference to sociodemographic profile. METHODOLOGY A community-based, observational study was conducted on adult 172 construction site workers in a university campus ...

Background: Nicotine is a major toxic component of cigarette smoke and it is a major risk factor in the development of functional disorder of several organ systems. Resveratrol (trans-3,5,4'-trihydroxystilbene; RES) is a naturally occurring polyphenol synthesized by a variety of plant species in response to injury, UV irradiation and fungal attack. It is present in grapes, berries, peanuts...

Increased activity of mesolimbic dopaminergic system within ventral tegmental area (VTA) due to nicotine results in psychologic dependence. It has been argued that function of dopamine receptors could by affected by ascorbic acid (AA). Furthermore, AA can decrease the withdrawal syndrome signs in addicted animals and may postpone the development of nicotine dependence. In the present study, the...

Background: Disturbances in maternal care have been associated with increased risk for drug abuse later in life. However, there has been little investigation of the effects of maternal separation (MS), a model of early life stress, on nicotine dependence, specifically during adolescence. In the present study, we aimed to investigate the effect of MS on nicotine-conditioned place preference (CPP...

Cigarette smoking is growing and nicotine is considered as the most adverse agent in the cigarette smoking. Nicotine is an alkaloid and forms 90% of alkaloids of cigarette. Nicotine is accountable for creating disorders and cancers such as lung cancer, heart disease and chronic lung disease. Nicotine can be considered as an autophagy and apoptosis inducer which can either directly or indirectly...

Smoking affects a widespread network of neuronal functions by altering the properties of acetylcholinergic transmission. Recent studies show that nicotine consumption affects ascending auditory pathways and alters auditory attention, particularly in men. Here we show that smoking affects language lateralization in a sex-specific way. We assessed brain asymmetries of 90 healthy, right-handed par...

Tobacco smoking has emerged as a risk factor for increasing the susceptibility to infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via increased expression of angiotensin-converting enzyme-2 (ACE2) in lung, linked disease 2019 (COVID-19) development. Given modifiable nature electronic cigarettes and delivery high concentrations nicotine, we investigate whether cigaret...

Aim: According to World Health Organization data, around 1.5 billion people in the world use tobacco products. Nicotine, most common of tobacco, is main psychoactive substance that causes addiction. Exposure nicotine during pregnancy increases risk low placenta weight, stillbirth, congenital heart disease, musculoskeletal defect. Antioxidants are used protect against teratogenic substances such...

Currently, 7.6% of the U.S. young adults aged 18–24 years old use e-cigarettes. This study piloted three methods Electronic Nicotine Delivery Systems (ENDS) cessation by measuring rates, motivational techniques that contributed to success, and participants’ changes after decreasing vape use. Participants were randomized into arms (nicotine replacement therapy (NRT) + behavioral support, vape-ta...