Progressive motor alterations and selective death of striatal medium spiny neurons (MSNs) are key pathological hallmarks Huntington’s disease (HD), a neurodegenerative condition caused by CAG trinucleotide repeat expansion in the coding region huntingtin (HTT) gene. Most research has focused on pathogenic effects resultant protein product(s); however, growing evidence indicates that expanded re...

The five most commonly recognized Harmful Algal Bloom related illnesses include Ciguatera poisoning, Paralytic Shellfish poisoning, Neurotoxin Shellfish poisoning, Diarrheic Shellfish Poisoning and Amnesic Shellfish poisoning. Although they are each the product of different toxins, toxin assemblages or HAB precursors these clinical syndromes have much in common. Exposure occurs through the cons...