نتایج جستجو برای: neuromyelitis optica
تعداد نتایج: 2294 فیلتر نتایج به سال:
Neuromyelitis optica (NMO) is a rare autoimmune disorder, distinct from multiple sclerosis, causing inflammatory lesions in the optic nerves and spinal cord. An autoantibody (NMO IgG) against aquaporin-4 (AQP4), a water channel expressed on astrocytes is thought to be causative. Peripheral production of the antibody is triggered by an unknown process in genetically susceptible individuals. Anti...
1Department of Neurology, Universidade Metropolitana de Santos, Santos SP, Brazil; 2Multiple Sclerosis Reference Center for the Coastal Region of the State of São Paulo, Santos SP, Brazil. Correspondence: Yara Dadalti Fragoso; Departamento de Neurologia, Universidade Metropolitana de Santos; Rua da Constituição 374; 11015-470 Santos SP Brasil; E-mail: [email protected] Conflict of interest: The...
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease characterized by antibodies against aquaporin-4 in up to 80% of the cases and even less in the NMO spectrum disorders, which may be difficult to distinguish from early multiple sclerosis. While immunosuppressive therapy should be introduced in definite NMO, treatment strategies of NMO spectrum disorders are less clearly defined...
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