BACKGROUND AND PURPOSE Hemodilution using modified hemoglobin solutions may reduce ischemic central nervous system injury. Purified diaspirin cross-linked hemoglobin (DCLHb) is a cell-free hemoglobin that is intramolecularly cross-linked between the two alpha subunits, resulting in enhanced oxygen offloading to tissues and increased half-life. In the present experiments, we evaluated the abilit...

It is considered that cognitive function and attention could affect walking, motion control, and proper conduct during the walk. To determine whether there is a difference in the quality of attention and cognitive ability in stroke patients and patients without neurological damage of similar age and education and to determine whether the connection of attention and cognition affects motor skill...

BACKGROUND Brain injury is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. We evaluated whether cardiopulmonary bypass (CPB) affects cerebrovascular resistance and plasma concentrations of adrenomedullin (AM), a vasoactive peptide regulating cerebral blood flow. METHODS We evaluated 50 infants (age <1 year) with congenital heart defects, matched ...

One hundred patients underwent elective cranioplasty for high velocity missile injury of the head during a 30-month-period study and investigation in Amiralmomenin Hospital affiliated to Iran University of Medical Sciences. Deep penetrating wounds were the most frequent injuries seen during this study. Three patients presented with massive bone defects and progressive neurological deficit ...

PURPOSE To investigate the efficacy of the integration of functional magnetic resonance imaging and diffusion-tensor imaging tractography data into CyberKnife radiosurgery for intracranial tumor management. MATERIALS AND METHODS Functional neuroimaging, anatomical magnetic resonance imaging, and computed tomography images of patients with brain lesions in critical areas were acquired before r...

A case of acute transverse myelitis associated with respiratory infection by Mycoplasma pneumoniae is described. Circulating antibodies to myelin were detected suggesting that mycoplasma related neurological damage is mediated by producing an immunological myelopathy.

An infant presented shortly after birth with signs suggestive of aortic coarctation. Echocardiography revealed an extensive aortic arch thrombus, not amenable to surgery. Thrombolytic agents reduced thrombus size, enabling survival, but failed to prevent neurological damage secondary to cerebral embolisation.

Five children with prenatal intracerebral damage associated with neonatal isoimmune thrombocytopenic purpura are described, and characteristic neurological features listed. These include optic hypoplasia which has not been previously documented in this condition.

Two patients developed transient rapid atrial fibrillation after a blow on the head. There was no evidence of neurological damage or organic heart disease on subsequent investigation. Neither patient was aware of the cardiac irregularity.

infective endocarditis can complicate with ischemic stroke. neurological complications develop in 20-40% of all patients with infective endocarditis. these are mainly due to vegetation embolism.this report represents a case of 30 years old female patient who presented with features of heart failure new york heart association (nyha) class iv with infective endocarditis and left hemiparesis. on e...