The pharmacological effects of the anesthetic alfaxalone were evaluated after intramuscular (IM) administration to 6 healthy beagle dogs. The dogs received three IM doses each of alfaxalone at increasing dose rates of 5 mg/kg (IM5), 7.5 mg/kg (IM7.5) and 10 mg/kg (IM10) every other day. Anesthetic effect was subjectively evaluated by using an ordinal scoring system to determine the degree of ne...

The total population of 11,865 children of compulsory school age resident on the Isle of Wight was studied to determine the prevalence of epilepsy, cerebral palsy, and other neurological disorders. With the use of reliable methods, children selected from screening of the total population were individually studied by means of parental interviews and questionaries, neurological examination and ps...

Exoskeleton gait rehabilitation is an emerging area of research, with potential applications in the elderly and people central nervous system lesions, e.g., stroke, traumatic brain/spinal cord injury. However, adaptability such technologies to user still unmet goal. Despite important technological advances, these robotic systems lack fine tuning necessary adapt physiological modification are no...

This research started from the premises of the existence of some possible relationships between indole and pineal peptide hormones and the somatic development, with participation of hypothalamic-pituitary complex. Experimental factors, which were the subject of the present paper, influenced the dynamics of corporal mass and fodder consumption, leading to the occurrence of some important structu...

Over the last few years, the importance of the resident intestinal microbiota in the pathogenesis of several gastro-intestinal diseases has been largely investigated. Growing evidence suggest that microbiota can influence gastro-intestinal motility. The current working hypothesis is that dysbiosis-driven mucosal alterations induce the production of several inflammatory/immune mediators which af...

The purpose of the present study was to investigate the relationship between somatotype components and maximal alactacid anaerobic power (MAAP) in trained subjects. The somatotype components (endomorphy: x = 2.66, S.D. = ± 0.78; mesomorphy: x = 5.45, S.D. = ±1.12; ectomorphy: x = 2.46, S.D. = ± 0.88) and total MAAP were measured in 40 male fencers (aged, x 21.79, S.D. = ± 3.97) in order to dete...

Those facts which should be included in any good textbook of physiology are reviewed, together with a systematic consideration of the subject matter of general physiology, the neuro-muscular mechanisms, the circulation, respiration, metabolism, excretion, reproduction, and the internal secretions. The book does not afford the more detailed information necessary for the advanced worker. Moreover...

The lawful continuous linear relation between movement time and task difficulty (i.e., index of difficulty; ID) in a goal-directed rapid aiming task (Fitts' law) has been recently challenged in reciprocal performance. Specifically, a discontinuity was observed at critical ID and was attributed to a transition between two distinct dynamic regimes that occurs with increasing difficulty. In the pr...

In neuro-rehabilitation, botulinum toxin (BTX) as adjunct to other interventions can result in a useful therapeutic tool treating disabled people. Other than spasticity, numerous motor and non motor disorders can complicate clinical course and hamper rehabilitative process of neurological impaired patients. A review of BTX use in treating muscular imbalance of children with obstetrical brachial...

Motivation: A locomotion control system could be used in active orthotics; orthotic braces with actuators attached to augment the muscles of a patient. This would allow patients with a variety of neuro-muscular ailments to walk in an easier, more natural way than is currently possible with passive orthotics. A similar technology could be used for prosthetics to assist patients with amputations ...