We have developed a polyimide based neural interface electrode to record nerve signals from the sciatic nerve of a rat. The neural interface electrode has a split-ring shape, with four protruding gold electrodes for recording, and two reference gold electrodes around the split-ring. The split-ring electrode can be opened up to encircle the sciatic nerve. The four electrodes can be bent to sit o...

While optogenetics offers great potential for linking brain function and behavior in nonhuman primates, taking full advantage of that potential will require stable access for optical stimulation and concurrent monitoring of neural activity. Here we present a practical, stable interface for stimulation and recording of large-scale cortical circuits. To obtain optogenetic expression across a broa...

It remains a challenge to efficiently extract spatialtemporal information from skeleton sequences for 3D human action recognition. Although most recent action recognition methods are based on Recurrent Neural Networks which present outstanding performance, one of the shortcomings of these methods is the tendency to overemphasize the temporal information. Since 3D convolutional neural network(3D...

The intracellular protozoan parasite Cryptosporidium parvum accumulates host cell actin at the interface between the parasite and the host cell cytoplasm. Here we show that the actin polymerizing proteins Arp2/3, vasodilator-stimulated phosphoprotein (VASP), and neural Wiskott Aldrich syndrome protein (N-WASP) are present at this interface and that host cell actin polymerization is necessary fo...

OBJECTIVE We characterized electrode stability over twelve weeks of impedance and neural recording data from four chronically-implanted Utah arrays in two rhesus macaques, and investigated the effects of glial scarring and interface interactions at the electrode recording site on signal quality using a computational model. APPROACH A finite-element model of a Utah array microelectrode in neur...

Neural Internet is a new technological advancement in brain-computer interface research, which enables locked-in patients to operate a Web browser directly with their brain potentials. Neural Internet was successfully tested with a locked-in patient diagnosed with amyotrophic lateral sclerosis rendering him the first paralyzed person to surf the Internet solely by regulating his electrical brai...

We propose and discuss an open source real-time interface that focuses in the vast potential for interactive sound art creation emerging from biological neural networks, as paradigmatic complex systems for musical exploration. In particular, we focus on networks that are responsible for the generation of rhythmic patterns.The interface relies upon the idea of relating metaphorically neural beha...

Epilepsy is common neurological disorder disease in the world. Electroencephalogram (EEG) can provide significant information about epileptic activity in human brain. Since detection of the epileptic activity requires analyzing of very length EEG recordings by an expert, researchers tend to improve automated diagnostic systems for epilepsy in recent years. In this work, we try to automate detec...