Risk prediction is an important field in applied statistics. For example, in clinical research, predicting the development of adverse medical conditions is the object of many studies. However, this concept is multi-disciplinary. Many published models exist to predict dichotomous outcomes, ranging widely from a model to predict winners in the NCAA basketball tournament to a recently published ri...

BACKGROUND Guidelines for primary prevention of cardiovascular diseases focus on prediction of coronary heart disease and stroke. We assessed whether or not measurement of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration could enable a more integrated approach than at present by predicting heart failure and enhancing coronary heart disease and stroke risk assessment. METHOD...

Diabetes mellitus is a prominent cause of death in the United States, with the presence of coronary artery disease (CAD) and cerebrovascular events contributing to a substantial portion of mortality among diabetic patients. Further, diabetes is considered to be a CAD equivalent, and the risk of incident adverse clinical events for diabetic individuals is estimated to be similar to nondiabetic i...

Abstract Background Liver and renal function evaluated by the model for end-stage liver disease (MELD) score, MELD excluding international normalized ratio (MELD_XI) score including sodium (MELD_sodium) have been considered predictors of adverse events patients with acute heart failure (AHF). However, prognostic value albumin (MELD_albumin) in AHF has not assessed. Methods A total 466 were pros...

Background: The purpose of this study was to explore whether consideration FIB levels might improve the predictive value ACEF score in patients with ACS. Methods: A total 290 ACS were enrolled study. clinical characteristics and MACE recorded. Results: Multivariate logistic regression analysis revealed that level (odds ratio=7.798, 95%CI, 3.44–17.676, P<0.001) SYNTAX ratio=1.034, 1.001–1.069...

BACKGROUND Chronic kidney disease (CKD) is an increasing public health issue. It is therefore potentially highly advantageous to identify patients at risk of accelerated renal progression and death. Neutrophil gelatinase-associated lipocalin (NGAL) is an established urinary biomarker for acute kidney injury, but it is not known whether adding urinary NGAL (uNGAL) measurements to conventional ri...