Erythropoietin (EPO) possesses generalized neuroprotective and neurotrophic actions. We tested the efficacy of recombinant human EPO (rhEPO) in preventing and reversing nerve dysfunction in streptozotocin (STZ)-induced diabetes in rats. Two days after STZ [60 mg/kg of body weight (b.w.), i.p.], diabetic animals were administered rhEPO (40 microg/kg of b.w.) three times weekly for 5 weeks either...

Moosa, A., and Dubowitz, V. (1971). Archives of Disease in Childhood, 46, 852. Slow nerve conduction velocity in cretins. The ulnar and posterior tibial conduction velocities were measured in 6 untreated and 3 treated cretins. In 4 of the untreated patients, the conduction velocity of both nerves was slower than normal; in 1 patient the ulnar and in the other the posterior tibial nerve conducti...

The cardio-ankle vascular index (CAVI) is used to test vascular function and is an arterial stiffness marker and potential predictor of cardiovascular events. This study aimed to analyze the relation between objective indices of diabetic polyneuropathy (DPN) and the CAVI. One hundred sixty-six patients with type 2 diabetes mellitus were included in this study. We used nerve conduction studies (...

Aim: To study the various electrophysiological changes in the motor conduction, sensory conduction and F wave latencies of acute Guillain-Barre Syndrome patients. Methods: Sixteen patients with acute GBS were included in this study. They were subjected to various nerve conduction studies (NCS) following standardized procedures. The mean values obtained for the various nerve conduction parameter...

Studies in experimental diabetic rat attribute the acute reversible nerve conduction defect as well as the early structural abnormalities of the node of Ranvier and myelinated axons to changes in nerve metabolism secondary to hyperglycaemia and activation of the pol yo1 pathway.’-8 The early readily reversible slowing of nerve conduction velocity in the diabetic rats correlates with a decrease ...

To investigate the physiological adjustments of textile workers exposed to high temperature environment, 10 workers with years of work experience and 12 students with rarely entering into workshop were chose to a hospital for blood test and nerve conduction velocity measurements. The blood test was to measure potassium content, sodium content, calcium content and bicarbonate content in particip...

BACKGROUND Metachromatic Leukodystrophy (MLD) is a rare, fatal demyelinating disorder with limited treatment options. Published outcomes after hematopoietic stem cell transplantation (HSCT) are scant and mixed. We report survival and function following HSCT for a large, single-center MLD cohort. METHODS Transplant-related data, survival and serial measures (brain MRI, nerve conduction velocit...

Introduction: Ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. As dexamethasone (Dex) has been shown to Prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. Methods: 36 male Wistar rats (200-250 gr) were chosen and divided randomly into 6 equal grou...

carpal tunnel syndrome (cts) is the most well-known and frequent form of median nerve entrapment, and accounts for 90% of all entrapment neuropathies. entrapment neuropathies of the ulnar nerve are relatively common with ulnar neuropathy at the elbow more prevalent than ulnar neuropathy at the wrist. the diagnosis of ulnar neuropathy at the elbow is usually confirmed in a relatively straight – ...

Single unit potentials were recorded from sural and medial gastrocnemius nerves. Action potential amplitude, integrated area and half-width (duration) were approximately proportional to conduction velocity, raised to the powers 1.5, 1 and -0.5 respectively with the sural nerve, and 2, 1.5 and -0.5 for the medial gastrocnemius nerve. These empirical relationships were applied to the computation ...