نتایج جستجو برای: neoplastic cell lines
تعداد نتایج: 1805913 فیلتر نتایج به سال:
background: increasing the complexity in modern radiotherapy techniques have increased the delivery time lowering consequently the treatment efficacy. through simulating the delivery time delay encountered in such techniques, its’ effect on two cancer cell lines and the compensating doses given to prevent such effect was investigated. materials and methods: f10b16 and 4t1 cancer cell lines were...
Apo2 ligand tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) is a member of the tumor necrosis factor family that interacts with cell surface "death receptors" (DR4 and DR5) to initiate programmed cell death. Apo2L/TRAIL also binds to "decoy" receptors (DcR1 and DcR2) that can antagonize its interaction with DR4 and DR5. In recent studies, Apo2L/TRAIL has been noted to prod...
The aim of this study is to search critical renin-angiotensin system (RAS) elements in myeloid leukemic cell lines. Human acute myeloid leukemia (AML) cell lines, KG-1 and HL-60, were cultured. We searched for the gene expression of the major RAS components in KG-1 and HL-60 cell lines by quantitative real-time polymerase chain reaction analysis (qRT-PCR). Angiotensin-converting enzyme I (ACE I...
Background: Ecballium elaterium is endemic to the northwestern Iran and its fruit is traditionally used for therapeutic purposes in Iran. The toxicological and phytochemical characteristics of the Iran’s Ecballium elaterium have not been investigated so far. Objective: Study on some toxicological and phytochemical features of the Iran’s Ecballium elaterium fruit 90% ethanol extract. Method: ...
بررسی تآثیر کورکومین بر بیان آکواپورین5 در سلول های سرطانی روده بزرگ انسان(ht-29) سرطان روده بزرگ جزو بیماری های خطرناک بوده و از نظر شیوع سومین سرطان شایع و دومین علت مرگ ومیر ناشی از سرطان در جهان محسوب می شود. خطرابتلا به این سرطان تحت تاثیر دو عامل محیطی وفاکتورهای ژنتیکی می باشد. آکواپورین ها، پروتئین های کانال آبی بوده که نقش مهمی را در انتقال آب در بافتهای اندوتلیالی و اپی تلیالی بر عهد...
Plasma cell dyscrasias are a group of entities characterized by neoplastic proliferation single clone plasma cells, typically producing monoclonal Immunoglobulin [1].
Three cell lines, spontaneously transformed in vitro, MWE-l and MWE-2 originating from C3Hf/Bi mouse whole embryos and NHLu-l originating from newborn syrian hamster lungs were obtained. These transformed cell lines were characterized by short generation time, marked aneuploidy in chromosome numbers and tumor induction in vivo. Histological appearance of the tumors induced by MWE-l was fibrosar...
c-myc expression, amplification, and rearrangement were studied in neoplastic hepatic nodules of rats after diethylnitrosamine treatment, in hepatocellular carcinomas induced by N-methyl-N-nitrosourea, and in tumorigenic liver cell lines derived from rat hepatocytes transformed by diethylnitrosamine in vivo. Steady-state levels of c-myc transcripts, as measured by Northern blot hybridization, w...
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