OBJECTIVE To study the incidence and outcome of systemic infections with methicillin sensitive (MSSA) and methicillin resistant Staphylococcus aureus (MRSA) infections in Australasian neonatal nurseries. METHODS Prospective longitudinal study of systemic infections (clinical sepsis plus positive cultures of blood and/or cerebrospinal fluid) in 17 Australasian neonatal nurseries. RESULTS The...

Early-onset neonatal infection (EONI) refers to an infection arising within first 72 h after birth. In August 2012, the National Institute of Health and Care Excellence (NICE) published guideline on the use of antibiotics to prevent and treat early-onset bacterial infection in newborn babies. Key recommendations included treating suspected EONI as quickly as possible and minimise antibiotic exp...

The leucocyte alkaline phosphatase (LAP) score was estimated in healthy and infected neonates. A leucocyte band count was also done simultaneously. The infected group showed a significant (P < 0.001) decrease in the LAP score and a significant (P < 0.001) increase in the band count. These findings are discussed.

Nosocomial or hospital acquired infections threaten the survival and neurodevelopmental outcomes of infants admitted to the neonatal intensive care unit, and increase cost of care. Premature infants are particularly vulnerable since they often undergo invasive procedures and are dependent on central catheters to deliver nutrition and on ventilators for respiratory support. Prevention of nosocom...

Neonatal Brain abscess is a rare sever neonatal infection requiring careful medical and neurosurgical intervention strategies to reduce morbidity mortality rates. Gram-negative bacterial agents are the most common pathogens involved in brain abscesses of neonates. The use wide spectrum antibiotics combination with drainage larger than 2.5 cm mainstay treatment. Colistin polymyxin antibiotic use...

The aims of this study were to determine the incidence of UTI in asymptomatic jaundiced neonates in the first two weeks of life , and to determine which historical and laboratory parameters are associated with UTI in those neonates.The study included 153 full -term jaundiced neonates less than two weeks old who had been admitted in hospital for management of jaundice. Work-up for hyperbilirubin...

Title:Polymicrobial bloodstream infections in the neonatal intensive care unit are associated with increased mortality: A case-control study

Background: In the recent decades, the prevalence of nosocomial infections in neonates has grown and almost 21% of preterm neonates experience these kinds of infections. Some factors were proposed to have a protective effect against neonatal infections through promoting the development of the immune system of the newborn. This study aimed to evaluate the efficacy of oral glutamine supplementati...

background it is known that risk factors related to neonatal bacterial sepsis are complex. objectives the current study aimed to determine the risk factors of neonatal sepsis. materials and methods this study was conducted on 1023 neonates admitted to neonatal intensive care units (nicus) in south sinai governorate hospitals from january 2010 till september 2014. demographic data of the neonate...

OBJECTIVE To estimate cause-of-death distributions in the early (0-6 days of age) and late (7-27 days of age) neonatal periods, for 194 countries between 2000 and 2013. METHODS For 65 countries with high-quality vital registration, we used each country's observed early and late neonatal proportional cause distributions. For the remaining 129 countries, we used multinomial logistic models to e...