abstract biofilm is a complex community of microorganisms residing within a polysaccharide and/or protein matrix. biofilm can be produced by microorganisms such as bacteria and fungi. both gram positive and gram negative bacteria have this ability. resistance of biofilm to antimicrobial agents is becoming a global issue. bacterial biofilms are important in various aspects such as chronic human ...

Much has been written and said in recent years regarding the classification and significance of the Enterobacteriaceae. These organisms, without a doubt, exceed all other gram-negative bacteria as etiologic agents of disease, and because of their predominance they have deserved the attention that they have received. With the emphasis placed on these fermenting bacteria, however, a dearth of inf...

BACKGROUND Gram-negative bacteria are associated with an increase in rates of antibacterial resistance. In most low- and middle-income countries such as Iran, there is no continuous surveillance system for antibiotic resistance. OBJECTIVE The purpose of this survey was to determine the pattern of antimicrobial sensitivity of gram-negative bacteria within 3 consecutive years at a nephrology wa...

New 3(2H)-pyridazinone derivatives containing a N'-benzyliden-acetohydrazide moiety at position 2 were synthesized. The structures of these newly synthesized compounds were confirmed by IR, 1H NMR, and MS data. These compounds were tested for their antibacterial, antifungal, antimycobacterial, and cytotoxic activities. The compounds 2-[4-(4-chlorophenyl)-6-(morpholin-4-yl)-3-oxo-(2H)-pyridazin-...

DW-224a showed the most potent in vitro activity among the quinolone compounds tested against clinical isolates of gram-positive bacteria. Against gram-negative bacteria, DW-224a was slightly less active than the other fluoroquinolones. The in vivo activities of DW-224a against gram-positive bacteria were more potent than those of other quinolones.

Background & Aim: In this study, is done during one-year research on blue–green and green algae for antimicrobial activity in Mashhad suburb. Aqueous, ether, and methanol extracts from 44 species blue – green algae and green algae were examined for antimicrobial properties against four bacteria (tow positive gram bacteria and tow negative gram bacteria) and tow fungous. Material & Methods: Amo...

Introduction: Bacterial meningitis is still one of the most dangerous infectious diseases and causes serious complications and mortalities in children. The aim of this study was to identify the most common of bacterial agents causing meningitis in children under 10 years old and to detect their resistance to antibiotics in patients who referred to the educational hospital of Hamadan. Materials...