Abstract PURPOSE Bevacizumab (Bev) treatment for recurrent glioblastoma ceases tumor angiogenesis, which changes appearance on Gd enhanced T1-weighted imaging. However, little is known about how non-angiogenic portions of are affected by Bev. Therefore, this study tested the hypothesis that patients with specific phenotypes outside contrast enhancement, as identified using autopsy tissue-based ...

OBJECTIVES The current study was designed to investigate the relationship between renal arterial structure and vessel remodeling in patients with atherosclerotic renal artery stenosis (RAS), compared with that seen in coronary artery disease (CAD). BACKGROUND The nature and the tissue characterization of atherosclerotic RAS lesions have not been fully explored. METHODS Gray scale and virtua...

Introduction:  Pressure  sores  refer  to  lesions  that  are  produced  while  a  constant  pressure  causes  necrotic  tissue to grow. The need for a better comprehension of the process has led researchers to artificial generation  of  pressure  sores.  Modeling  the  mechanical  behavior  of tissue  will  provide  a better understanding  of this  process as well as a more suitable selection ...

A 30-year-old woman presented with a four-week history of abdominal swelling. She had a long history of hormonal treatment for infertility but pregnancy test was negative. On ultrasound she was seen to have a large volume of ascites which was found to be haemorrhagic on insertion of an ascitic drain. Ascitic fluid cytology, culture and tuberculosis PCR were negative. An MRI pelvis confirmed lar...

We compared gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) enhanced T1-weighted images (T1-Gd) with the histopathological findings in 13 patients with bone or soft tissue sarcomas. Signal intensity of the viable tumor tissue was increased in T1-Gd in 92% of the patients. The necrotic or cystic areas in the tumor were not enhanced, rendering them distinctly. The degree of enhancement of...

Skin perfusion pressure (SPP) is the perfusion pressure at the skin level, and it can serve as an index of peripheral circulation in the skin and subcutaneous tissue. We report a 78-year-old man with critical limb ischaemia who, despite having undergone several catheter interventions, still had severe ulcers with exposed bone on his right foot. We performed transmetatarsal amputation. The tissu...

Spinal cord nematodiasis epidemiologically, clinically, and histologically consistent with Parelaphostrongylus tenuis infection was noted in two flocks of sheep. Spinal cords from two sheep with active infection and one from a partially recovered animal were studied in an effort to determine the sequence of lesions following larval invasion of the central nervous system. In the former two sheep...

Spinal cord (SC) contusion in rats yields an experimental model of SC trauma in humans. This model has often been criticized for its lack of reproducibility. Both histological observations and functional recovery cannot be reproduced consistently. The recent demonstration that homotopic fetal transplants in newborn and adult SC can improve locomotion, discloses the ability of fetal neural tissu...

In the Scots pine (Pinus sylvestris L.) seed, embryos grow and develop within the corrosion cavity of the megagametophyte, a maternally derived haploid tissue, which houses the majority of the storage reserves of the seed. In the present study, histochemical methods and quantification of the expression levels of the programmed cell death (PCD) and DNA repair processes related genes (MCA, TAT-D,...

BACKGROUND AND PURPOSE The composition of carotid atherosclerosis was visualized by using 3D MRI at high resolution with 200-micrometer (3) voxels. Magnetic resonance signal characteristics were correlated with plaque components, including collagenous cap, necrotic core, and calcification, to define resolution and other requirements for future clinical carotid MRI. METHODS Twenty-one en bloc ...