Severe myocardial necrosis was produced in virgin Sprague-Dawley rats without preexisting arteriosclerosis and in breeder Sprague-Dawley rats with various degrees of arteriosclerosis by giving two subcutaneous injections of isoproterenol; the virgin rats received 50 mg/100 g and the breeder rats 25 mg/100 g body weight. Breeder rats withstood the stress and shock of myocardial necrosis with few...

Bacterial, mechanical, or chemical irritation to the pulp may result in tissue necrosis and release of disintegration by-products that may penetrate tubules and discolor the surrounding dentin. The degree of discoloration is directly related to how long the pulp has been necrotic. The longer the discoloration compounds are present in the pulp chamber, the greater the discoloration. Such discolo...

Small-vessel vasculitides associated with the presence of antineutrophil cytoplasmic antibodies in the serum are characterized by inflammation and necrosis of small vessels. A pauci-immune necrotizing crescentic glomerulonephritis typically occurs when there is renal damage. Pathogenesis of these diseases remains unclear although infectious, genetic and environmental factors have been involved....

2 Department of Orthopaedic Surgery, Harborview Medical Center, Seattle, WA Femoral neck fractures are associated with a high degree of morbidity in patients of any age, but urgent attention is given to fractures in the young patient due to complications such as femoral head osseous necrosis, fracture nonunion, or post traumatic hip arthritis. Anatomic open reduction with stable internal fixati...

In a study of cytokine production ex vivo by Borrelia burgdorferi-stimulated peripheral blood mononuclear cells from 27 patients with culture-positive erythema migrans, production of inflammatory cytokines predominated, particularly gamma interferon and, to a lesser degree, tumor necrosis factor alpha. In contrast, with the exception of interleukin-13, anti-inflammatory cytokine production was ...

BACKGROUND/AIM   Intrusive luxation in the permanent dentition is an uncommon injury but it is considered one of the most severe types of dental trauma because of the risk for damage to the periodontal ligament, pulp and alveolar bone. Management of intrusive luxation in the permanent dentition is controversial. The purpose of this study was to evaluate pulp survival and periodontal healing in ...

BACKGROUND: Examining corpses recovered from the water often poses challenges in forensic medical evaluation.
 AIM: To propose a clarifying set of differential diagnostic features characteristic fatal cold injury low-water temperature conditions.
 MATERIALS AND METHODS: Clinical observations, examination patients who died general hypothermia and drowning ice water.
 RESULTS: A co...

background: inflammatory response following surgical trauma has long been a matter of study. results, however, have been varied. we sought to assess changes in the levels of proinflammatory and anti-inflammatory cytokines in patients undergoing laparoscopic and open cholecystectomy and their impact on the clinical outcome of patients concerning the postoperative pain score. methods: the study i...

2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) is a by-product o f t he trichlorophenol (herbicide) production and is also produced through a variety of combustion processes. it appears that tcdd is a ubiquitous chemical, particularly in industrialised countries, and the liver is the target organ of its toxicity. the prominent hepatotoxic effect of tcdd is progressive centrilobular necrosis. the is...