Objectives: The use of a biomaterial scaffold can improve the healing process bone defects. Using radiologic and ultrasonographic methods, this study aimed to evaluate effects zeolite/collagen nanocomposite nanohydroxyapatite (nHA) scaffolds on defect in rabbit femur. Materials Methods: Twenty-eight mature male New Zealand white rabbits were classified into four equal groups (n=7 each). In firs...

Introduction: Drugs and biocompatible nanoparticles have raised significant potential in advancing the bone regeneration. Electrospinning technology enables full realization of value drugs nanoparticles. Methods: In this study, we successfully fabricated core–sheath nanofibers solely composed polycaprolactone (PCL) polymer. Simvastatin (SIM) was confined to core while nanohydroxyapatite (nHA) l...