Drug delivery researches has drawn tons of attention to achieve the targeted therapies that work for many diseases. Nanogels, a type polymeric hydrogels with nanoscale size, are promising materials drug applications. However, current polymers used synthesizing nanogels lack in biocompatibility, stability, and low biosafety. This review focus on mannan-based high loading capacity, multifunctiona...

In the present study, smart responsive microgels are synthesized from a series of alternative monomers, which less common in micro- and nanogel research. Their swelling behavior is studied by means photon correlation spectroscopy Fourier transform infrared spectroscopy. addition, these monomers used to make copolymer microgels. line with previous results for such particles work observes linear ...

The inclusion complex is one way to enhance active substance solubility, affecting medicine dissolution and penetration. formed by utilizing b-cyclodextrin as the host of compounds. Ibuprofen (2-(4-isobutyl-phenyl)propionate) a propionate acid derivative classified in class II Biopharmaceutic Classification System, which has low dissolutions high permeability. This study aims develop nanogel co...

Recently, specific attention has been paid to aptamers, short DNA or RNA, as a tool for cancer diagnosis and therapy. In the present study MCS nanogels were prepared by Myristate: chitosan at 1:9 ratio and were characterized by several techniques. A selected ssDNA aptamer(Apt) capable of detecting LNCaP cells was linked to Myristilated chitosan nanogels (Apt-MCS) by glutaraldehyde and loaded wi...

We theoretically and experimentally analyze the formation of thick Purple Membrane (PM) polyacrylamide (PA) films by means of optical spectroscopy by considering the absorption of bacteriorhodopsin and scattering. We have applied semiclassical quantum mechanical techniques for the calculation of absorption spectra by taking into account the Fano effects on the ground state of bacteriorhodopsin....