This work analyzes the dispersion of two highly hydrophobic actives, (9Z)-N-(1,3-dihydroxyoctadecan-2-yl)octadec-9-enamide (ceramidelike molecule) and 2,6-diamino-4-(piperidin-1-yl)pyrimidine 1-oxide (minoxidil), using oil-in-water nanoemulsions with aim preparing stable safe aqueous-based formulations that can be exploited for enhancing penetration active compounds through cosmetic substrates....

During the production process, water phase incursion into reservoir causes blocking damage and seriously affects of tight gas reservoirs. Recently, nanoemulsions have been used as highly effective removing agents in field, but their mechanism is still unclear. In this research, a series with different droplet sizes were synthesized, performance was intensively investigated. To begin, relationsh...

     The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it i...

     The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it i...

Objective: To Formulate and Evaluate Nanoemulsions of Caffeic acid to overcome its poor aqueous solubility bioavailability. Methods: The caffeic nanoemulsions were prepared by spontaneous emulsification method through selection oil phase based on studies surfactant co-surfactant screening the basis their ability. components selected maximum in various media such as isopropyl myristate phase, tw...

Brinzolamide (BZ) is an intraocular pressure reducing agent with low bioavailability. The purpose of the present study was to overcome this issue by development of BZ containing nanoemulsions (NEs) as an ocular drug delivery system with desirable therapeutic efficacy. Brinzolamide NEs were prepared by the spontaneous emulsification method. Based on initial release studies, twelve formulations w...

Nanoemulsions are alternative means of incorporating functional components into systems. This research aims to model the effect African catfish mucilage (ACM) concentrations on particle size (PS) stable oil-in-water (O/W) nanoemulsions formulated by ultrasonication. A D-optimal mixture design was used study influence three (MCs) ACM, oil, and water PS. Morphology PS were determined with Cryo-TE...