The limited induction of spermidine/spermine N1-acetyltransferase (SSAT) activity has been implicated as an important determinant of the reduced response to the spermine analogue N1,N12-bis(ethyl)spermine (BESpm) by the cisplatin or cis-diamminedichloroplatinum(II) (cDDP)-resistant human ovarian carcinoma cell line (C13*). We checked whether or not under conditions of SSAT overexpression, enzym...

Currently, one of the loci communes economic history is that New Deal was right cocktail state-mandated policies to pull US economy out Great Depression begun in 1929. The relevance this interpretation has increased tremendously since crisis 2008 many compare with There a quasi-general demand for new Deal. This view contended by Austrian School Economics and other free-market oriented thinkers....

Ammonia (NH3) is an important component of the nitrogen (N) cycle in terrestrial ecosystems and is a significant atmospheric pollutant. Results from studies of ammonia emissions from semi-arid grasslands have been infrequently reported although these emissions may be increasing rapidly with a subsequent increase in atmospheric N deposition. Moreover, whether N deposition regimes (fertilization ...

Vesicular arbuscular mycorrhizae (VAM) fungi commonly infect plant roots, forming beneficial symbiotic relationships. The primary benefits of VAM plants are the enhanced acquisition and recycling of nutrients, particularly P, as well as soil moisture. This study compared the relationship between soil and leaf chemical elements of sugarcane variety N12 with low and high % mycorrhization (%myc). ...

Pseudomonas putida KT2440 encodes 23 alternative sigma factors. The fliA gene, which encodes σ(28) , is in a cluster with other genes involved in flagella biosynthesis and chemotaxis. Reverse transcriptase-PCR revealed that this cluster is comprised of four independent transcriptional units: flhAF, fleNfliA, cheYZA and cheBmotAB. We generated a nonpolar fliA mutant by homologous recombination a...

The polyamine analogue, N1,N12-bis(ethyl(-spermine (BESPM), is known to suppress ornithine and S-adenosylmethionine decarboxylase levels, deplete intracellular polyamine pools, and inhibit cell growth. Among human melanoma cell lines, MALME-3 cells were found to be typically sensitive to the antiproliferative activity of the BESPM, whereas LOX cells were atypically insensitive to the analogue. ...

The spermine analogues, N1,N12-bis(ethyl)spermine (BESPM), N1,N11-bis(ethyl)norspermine (BENSPM), and N1,N14-bis(ethyl)-homospermine (BEHSPM) behave similarly in down-regulating the key polyamine biosynthetic enzymes, ornithine and S-adenosylmethionine decarboxylase, but differ distinctly in their abilities to induce the polyamine catabolic enzyme, spermidine/spermine-N1-acetyltransferase; BENS...

Two new species of the freshwater cyclopoid genera Eucyclops are described, Eucyclops tziscao sp. n. and E. angeli sp. n. Both species belong to the serrulatus-group defined by morphological features such as: the presence of distal spinules or hair-like setae (groups N1 and N2) on frontal surface of antennal basis; the fourth leg coxa with a strong inner spine that bears dense setules on inner ...

A number of members of the G protein-coupled receptor class of cell surface receptors are 'orphans' with no known endogenous ligand. One of these orphan receptors is GPR61; there are little data about its expression in human cells and tissues. In this study, we investigated the post-translational modification of GPR61 by N-glycosylation at an identified consensus N-glycosylation site (N12) and ...

Aim: The aim of this study was to investigate the relationship between sleep of healthy infants and their mother’s parenting stress in Japan. Methods: Cross-sectional study. Data obtained from 48 healthy mothers and their infants aged from 6-month old to 24-month old were studied. The mothers completed questionnaires including the Parenting Stress Index Short Form (PSI Short Form), and infant’s...