The main objective of this study was to prepare sustained release metformin hydrochloride microcapsules by the Wurster fluidized bed and to obtain the optimized coating process and formulation. Fine microcapsules without agglomeration were obtained in a continuous coating process with the atomization air pressure of 0.2Mpa and an appropriate coating speed temperature. With other design variable...

Dopamine is an excellent and flexible agent for surface coating of inorganic nanoparticles and contains unusually high concentrations of amine groups. In this study, we demonstrate that through a controlled coating of a thin layer of polydopamine on the surface of α-Fe(2)O(3) in the dopamine aqueous solution, followed by subsequent carbonization, N-doped carbon-encapsulated magnetite has been s...

The Trillium coating is designed to minimize adsorption of protein and the attachment of cells and other particles. The present study was undertaken to investigate the effect of surface coating on the adhesion of thrombotic components (activated platelets, white blood cells and fibrin) to the surface of a clinically used oxygenator. Twenty patients undergoing elective coronary artery bypass gra...

Experimental studies suggest a reduced neointimal tissue proliferation in vascular stainless steel stents coated with gold. This prospective multicenter trial evaluated the impact of gold coating on neointimal tissue proliferation in patients undergoing elective stent implantation. The primary end point was the in-stent tissue proliferation measured by intravascular ultrasound at 6 months compa...

In this work, novel thin film composite membranes (TFCs) of poly (ether-6-block amide) (Pebax-1657) on a polyvinyl chloride (PVC) ultrafiltration membrane as support were prepared using inclined coating method for CO2 separation. Investigating the effects of top selective layer thickness formed by controlling the coating angle (15-60°) and polymer solution concentration (5-10 wt.%), ...

Experiment was conducted to evaluate the effect of different levels of egg yolk for coating and storing spermatozoa. Ejaculates were collected from four rams. In each session, second ejaculates (n=4) were collected in a tube containing 1 mL coating buffers which were prepared by 10, 15 or 20% egg yolk plus Tris-fructose. Samples were pooled, centrifuged and the supernatant removed in the labora...

Background and Aim: This study aimed to assess the effect of finishing and polishing time, technique and surface coating on microleakage of encapsulated restorative resin modified glass ionomer (RMGI). Materials and Methods: In this in vitro study, 40 freshly extracted human premolars were selected. Two standard class V cavities were prepared on the buccal and lingual surfaces of each tooth. T...

A novel in-line technique utilising pulsed terahertz radiation for direct measurement of the film coating thickness of individual tablets during the coating process was previously developed and demonstrated on a production-scale coater. Here, we use this technique to monitor the evolution of tablet film coating thickness and its inter-tablet variability during the coating process under a number...

PURPOSE Magnetic submicron particles (MSPs) are pivotal biomaterials for magnetic separations in bioanalyses, but their preparation remains a technical challenge. In this report, a facile one-step coating approach to MSPs suitable for magnetic separations was investigated. METHODS Polyethylene glycol) (PEG) was derived into PEG-bis-(maleic monoester) and maleic monoester-PEG-succinic monoeste...

OBJECTIVES This study investigated the immediate and sustained effect of sodium trimetaphosphate (TMP) and sodium hexametaphosphate (HMP) associated or not with fluoride (F) on hydroxyapatite (HA) dissolution using an erosion-like model, considering as well as the influence of salivary coating. DESIGN Baseline dissolution rates were determined for HA discs using a pH-stat system. In the first...