Since Knox and Grossman demonstrated the excretion by man of the 6-pyridone of N’-methylnicotinamide (hereafter referred to as the pyridone) in appreciable amounts after the ingestion of nicotinamide (2), it became necessary to devise a method for its quantitative estimation in urine. Knox and Grossman isolated the compound from human urine and described its properties, including its ultraviole...

In the title compound, C(14)H(14)N(2)O(2), the dihedral angle between the two benzene rings is 9.67 (10)°. Two intra-molecular O-H⋯N and N-H⋯N hydrogen bonds involving the hydr-oxy and amino groups generate S(6) and S(5) ring motifs, respectively. In the crystal structure, N-H⋯O hydrogen bonds link neighboring mol-ecules. Mol-ecules are also stacked in a head-to-tail fashion along the c axis th...

In the title compound, C(13)H(13)Cl(2)N(3)OS, the thia-zole and benzene rings are roughly parallel to one another in two layers [dihedral angle = 5.08 (2)°] because the N-C-C-N-C chain that links the two rings is folded [N-C-C-N torsion angle = 12.0 (2)°] rather than fully extended. An intra-molecular N-H⋯N inter-action occurs. In the crystal, weak inter-molecular N-H⋯N and C-H⋯O inter-actions ...

In the title compound, C(14)H(16)N(2)O(2)S, the two aromatic rings make a dihedral angle of 13.9 (1)°. The crystal structure is stabilized by both inter- and intra-molecular N-H⋯O, C-H⋯O and C-H⋯N hydrogen bonds.

In the title mol-ecule, C(11)H(9)N(3)O(2)S, the thio-phene and benzene rings form a dihedral angle of 17.68 (9)°. The thio-phene S atom and the imine N atom are syn with respect to each other. In the crystal, N-H⋯O and N-H⋯N hydrogen bonds connect mol-ecules, forming a two-dimensional network parallel to (10-1).

In the crystal structure of the title compound, C(10)H(8)BrN(3)O, the dihedral angle between the two pyridine rings is 2.48 (2)°. A weak intramolecular N-H⋯O hydrogen bond is present.

The title compound, C(21)H(20)N(2)O(2), a Schiff base ligand, contains two independent mol-ecules (A and B) in the asymmetric unit, with similar conformations. In mol-ecule A, the central benzene ring forms dihedral angles of 30.79 (13) and 23.56 (13)°, respectively, with the amino and benzyl benzene rings, while in mol-ecule B these angles are 32.30 (13) and 13.13 (12)°. The mol-ecular structu...