CO binds at a cluster Fe that is bridged to the Ni. Methyl transfer to the Ni is then followed by attack on the bound CO, forming an acetyl adduct, which might migrate from Fe to Ni. Transfer of the acetyl group to CoA completes the catalytic cycle. Alkyl attack on metalbound CO is a well-precedented organometallic process that has been extensively studied (21). Usually the CO binds to the same...

7-Hydroxycoumarine undergoes a smooth reaction with alkyl propiolates in the presence of triphenylphosphine (15 mol%) to produce the corresponding alkyl (E)-3-((2-oxo-2H-chromen- 7-yl)oxy)acrylate in good yields. When the reaction was performed by 3-hydroxyquinoline similar alkyl acrylates were obtained.

A simple chemical procedure for synthesis of 1-O-alkyl-(rac or sn)-glycero-3-phosphocholine (alkyl analog of lysophosphatidylcholine, II) and platelet activating factor (PAF), 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (III) has been described. The key step of the method is the decomposition of 1-O-hexadecyl-3-diazohydroxyacetone (A. K. Hajra, T. V. Saraswathi and A. K. Das, 1983. Chem. Phy...

The N-R-quinolinyl-8-amino ligands HL(1-3) (R = 2,6-(i)Pr(2)C(6)H(3) (HL(1)), 2,6-Et(2)C(6)H(3) (HL(2)), 2,6-Me(2)C(6)H(3) (HL(3))) have been prepared, which reacted readily with one equiv. of rare earth metal tris(alkyl)s to afford the corresponding bis(alkyl) complexes L(1)Y(CH(2)SiMe(3))(2)(THF) (1) and L(1-3)Lu(CH(2)SiMe(3))(2)(THF) (2-4) via alkane elimination. Contrastingly, treatment of ...

A new synthetic pathway to various mono-alkyl-substituted phosphinoboranes HRP–BH2–NMe3 has been developed. The route starting from alkyl halides and NaPH2 followed by metalation salt metathesis is performed in a one-pot procedure leads higher yields purity of the resulting phosphinoboranes, as compared previously reported routes. Additionally, scope accessible compounds could be expanded short...

A highly efficient method for the synthesis of N-alkyl isatins starting from N-alkyl 2-bromo or 2-chloro acetanilides is described. The starting materials are easy to prepare and the yields of isatins are generally high. Operationally the reaction is very simple to run. Even though best results were obtained with a catalytic amount of CuI, the reactions of N-alkyl 2-bromo acetanilides actually ...

The effect of modifying the N-aryl substituent (aryl = mesityl vs. m-xylyl) of the phosphinoamide ligands linking Zr and Co in tris(phosphinoamide)-linked heterobimetallic complexes has been investigated. Treatment of the metalloligand ((i)Pr2PNXyl)3ZrCl (2) (Xyl = m-xylyl) with CoI2 affords the iodide-bridged product ICo((i)Pr2PNXyl)2(μ-I)Zr(η(2-i)Pr2PNXyl) (3) rather than the C3-symmetric iso...

A series of benzothiazol-2-yl-dithiocarbamates 3a-d along with their copper complexes 4a-c were synthesized via the reaction of suitable alkyl, aralkyl or heteroaryl halides with the sodium salt of benzothiazol-2-yl-dithiocarbamic acid, followed by complexation with copper sulphate. N-(4-Acetyl-5-aryl-4,5-dihydro-1,3,4-thiadiazol-2-yl)-N-benzothiazol-2-yl-acetamides 7a-c were synthesized by cyc...

N-Acetylation of (2,3,4,6-tetra-O-acetyl-a-D-glucopyranosyl) (2,3,4,6-tetra-0-acetyl-/?-D-glucopyranosyl)amine or bis(2,3,4,6-tetra-0-acetyl-/3-D-glucopyranosyl)amine afforded N-acetyl-bis(2,3, 4,6-tetra-0-acetyl-/3-D-glucopyranosyl)amine; deacetylation of the latter gave Af-acetyl-di-/3-Dglucopyranosylamine. Similarly, TV-acetylation of bis(2,3,4-tri-0-acetyl-/3-L-rhamnopyranosyl)amine led to ...