Abstract Instrumental data from the pre–Industrial Revolution period are important to ­understand climate change. In this paper, observations made by French missionary J. Amiot in present-day central Beijing during 1757–62 were processed and analyzed. The represent earliest continuous dataset of meteorological records found China that have been digitized recently. Comparisons between annual tem...

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The title compound, [Cu(C(8)H(7)N(3))(2)(H(2)O)](3)[As(2)Mo(18)O(62)], consists of two subunits, viz. an α-Dawson-type [As(2)Mo(18)O(62)](6-) anion and a complex [Cu(C(8)H(7)N(3))(2)(H(2)O)](2+) cation. The copper(II) ion (site symmetry .2) is penta-coordinated in a distorted square-pyramidal manner by four N atoms from two chelating 3-(2-pyrid-yl)pyrazole ligands in equatorial positions and on...

Several adult-onset neurodegenerative diseases are caused by genes with expanded CAG triplet repeats within their coding regions and extended polyglutamine (Qn) domains within the expressed proteins. Generally, in clinically affected individuals n >/= 40. Glyceraldehyde 3-phosphate dehydrogenase binds tightly to four Qn disease proteins, but the significance of this interaction is unknown. We n...

The inhibitor of growth family, member 3 (ING3) protein may be capable of blocking the cell cycle via activating p53-transactivated promoters of p21 and Bcl2-associated X protein, and may induce apoptosis via a Fas/caspase-8-dependent signaling pathway. In the present study, immunohistochemistry was performed in order to characterize the expression profile of ING3 protein in tissue microarrays ...