A rest–pause (RP) technique involves performing one or more repetitions at high resistance to failure, followed by a short rest before repetitions. These techniques can affect neuromuscular conditions and fatigue changing the time between This study compared effect of 12 weeks RP traditional training (TRT) on myokines (myostatin (MSTN), follistatin (FLST) insulin-like growth factor-1 (IGF-1)) f...

Chronic kidney disease (CKD) is a prevalent worldwide public burden that increasingly compromises overall health as the progresses. Two of most negatively affected tissues are bone and skeletal muscle, with CKD impacting their structure, function activity, impairing quality life these patients contributing to morbidity mortality. Whereas in this population has conventionally been associated min...

Background & Aim Sarcopenia is frequent in cirrhosis and associated with unfavourable outcomes. The role of the gut-liver-muscle axis this setting has been poorly investigated. aim study was to identify gut microbiota, metabolic inflammatory signatures sarcopenia cirrhotic patients. Methods Fifty patients assessed for presence by quantification muscle mass strength were compared age- sex-matche...

Significance: The prevalence and incidence of age-related neurodegenerative diseases (NDDs) tend to increase along with the enhanced average world life expectancy. NDDs are a major cause morbidity disability, affecting health care, social economic systems significant impact. Critical Issues Recent Advances: Despite worldwide burden ongoing research efforts underlying molecular mechanisms involv...

The use of endurance regimens could be improved by defining their respective effectiveness on aerobic fitness and brain health that remains controversial. We aimed at comparing work-matched high-intensity interval training (HIIT) with moderate-intensity continuous (MICT) performance muscular plasticity markers in healthy rats. Cognitive functions were also investigated following the 8-week trai...

Abstract Myokine abundance and function have not been thoroughly evaluated in beef cattle. Many myokines shown to a substantial impact on the health well-being of mammals. While interleukin 6 (IL-6) is known immune cytokine, it also classified as myokine mice produced from muscle contraction post-exercise. IL-6 linked hypertrophy through action increasing glucose uptake stimulating satellite ce...

Aging is associated with both muscle weakness and a loss of muscle mass, contributing towards overall frailty in the elderly. Aging skeletal muscle is also characterised by a decreasing efficiency in repair and regeneration, together with a decline in the number of adult stem cells. Commensurate with this are general changes in whole body endocrine signalling, in local muscle secretory environm...