whooping cough (pertussis) is a highly contagious disease of the human respiratory tract, which is caused by bordetella pertussis. reemerge of pertussis in some highly immunized populations and divergency in gene order among several b. pertussis strains promoted this research to study the change of pertussis toxin (pt) and lipopolysacharide levels in response to the different environments. this...

results findings showed that the genotype -607a/a is associated with the susceptibility to chronic hepatitis b. furthermore, allele c at position -137 is suggested to play a protective role against development of chronic hbv infection. conclusions host genetic factors play an important role in determining the outcome of hbv infection. it is suggested that il-18 genotype -607 a/a is associated w...

Field experimental observations from GPS Radiosonde, 3 meteorological towers and 16 automated weather stations were employed to validate boundary layer wind field simulations made with Weather Research and Forecasting (ARW) model in the tropical coastal Kalpakkam region in southern India during the Round Robin Exercise (RRE) field experiment period (14 -24 September 2010). Three nested domain w...

BACKGROUND Little data exist on the safety of elective breast surgery following breast conservation therapy. OBJECTIVES The authors evaluate their experience performing reduction mammaplasties and mastopexies in previously irradiated breasts. METHODS A retrospective chart review was conducted of all reduction mammaplasties and mastopexies in previously irradiated breasts performed by the 2 ...

Ultraviolet-B radiation (UV-B) and cold limit the growth development of plants, which generates changes in gene expression. This allows plants to respond stress through regulatory proteins, such as transcription factors, that activate or repress expression stress-response genes. RNA-Seq data WGCNA analyses were utilized identify hub Our study found a total 25, 24, 29 factors at different time p...

Background and Objective: The drug resistance mutations are key elements in the failure of long-term treatment of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections. The mutation in the YMDD motif in the P gene of HBV is the most critical factor in antiviral drug (especially lamivudine) resistance. This study aimed to assess the YMDD motif and other polymerase gene mutati...

Background: Genetic polymorphism of milk proteins has been associated with composition, manufacture, and traits of milk. Caseins are the most important milk proteins whose genes are strongly linked and inherited as a raceme. κ-casein which is a quantitatively minor constituent of bovine milk is thought to play a critical role in organization, fixation and aggregation of casein micelles and firm...

background and objectives : economic constraint of diseases arising from salmonella typhimurium causes the study of this zoonotic organism more important. most studies on identification and characterization of s. typhimurium are conducted at dna level. flagellin genes (flic and fljb genes encoding phase-1 and phase-2 flagella, respectively) are useful as a model system for studying genetic diff...

Objective(s): Genetic analysis of two consanguineous Pakistani families with localized autosomal recessive hypotrichosis was performed with the goal to establish genotype-phenotype correlation. Materials and Methods: Genomic DNA extraction had been done from peripheral blood samples. Extracted DNA was then subjected to PCR (polymerase chain reaction) for amplification. Linkage analysis was perf...

Brucella melitensis, as a pathogenic gram-negative intracellular bacterium, causes brucellosis in animals and humans. According to literature, the B. melitensis outer membrane protein 31 (Omp31) is considered as an important vaccine candidate against brucellosis. The aim of the current study was to compare three different expression constructs containing B. melitensis Omp31 antigen using bioinf...