نتایج جستجو برای: mycophenolate mofetil
تعداد نتایج: 3651 فیلتر نتایج به سال:
Mycophenolate mofetil (MMF) is a potent immunosuppressive agent initially used in renal transplantation, but positive experience in the field of solid organ transplantation has made the drug attractive for the treatment of several autoimmune diseases. MMF targets the de novo purine biosynthesis pathway by noncompetitive inhibition of inosine monophosphate dehydrogenase, acting against the proli...
Pulmonary hypertension (PH) is a life-threatening complication of several, different connective tissue diseases, including systemic lupus erythematous (SLE), systemic sclerosis, and rheumatoid arthritis. PH can present early in SLE. The severity does not correlate with other organ disease activity or with disease duration. It is still debatable whether immunosuppressive therapy is useful for PH...
Kidney transplantation is now firmly established as the treatment of choice for most patients with End Stage Renal Disease. The short-term outcomes of renal transplantation have dramatically improved over the past several decades; in a large part, this success is due to improvements in immunosuppression and post transplantation medical care. The goal of immunosuppressive strategies in transplan...
Cutaneous leishmaniasis is a parasitic infection caused by flagellate parasite of the genus Leishmania. It most often zoonotic disease transmitted bite sandflies. We report case renal transplant recipient who presented with cutaneous leishmaniasis. A 32-year-old man from Gafsa was received kidney in September 2017 living related donor (5 HLA identities). The induction immunosuppression based on...
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