Introduction: Chemokine receptors are found on the surface of stem cells. There have been 19 distinct chemokine receptors described in mammals. Chemokines are major players in migration and homing. Therefore, changes in their levels or function can help us to increase the migratory potential of these cells. Valproic acid differs in structure from other drugs in common use. The way in which Va...

Inflammatory bowel disease (IBD) is a severe inflammatory condition in the colon. To date, clinical solutions for this disease have been limited. Mesenchymal stem cells (MSCs), multipotential cells with immune regulation and anti-inflammatory functions, have been applied to treatment of IBD. However, the therapeutic effectiveness of MSCs still needs to be improved. Here, we were interested in w...

In the present study we have isolated and identified mesenchymal stem cells (MSCs) from the exfoliated deciduous teeth dental pulp (DP-MSCs), as plastic-adherent, spindle-shaped cells with a high proliferative potential. Immunophenotype analyses revealed that DP-MSCs were positive for mesenchymal cell markers (CD90, CD44, CD105, STRO-1, vimentin and α-SMA), and negative for hematopoietic stem c...

This review is focused the evolution of mesenchymal stem cells (MSCs) and their clinical applications in rheumatology. MSCs have significant properties immunomodulatory by suppressing T- B-cell proliferation, dampening generation mature myeloid dendritic cells, inhibiting cytokine production cytotoxic activity natural killer they capacity to engulf apoptotic cells. work addresses results vitro ...

introduction: the field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. stem cell therapy seems to be a new treatment option for some diseases. so, tracking the distribution of stem cells is crucial to their therapeutic use. based on this fact we labeled human mesenchymal stem cells (mscs) with 111in- oxine for the first time in our coun...

The review discusses the pathogenetic mechanisms of development respiratory infection COVID-19 and clinical use cell technologies based on mesenchymal stem cells (MSCs). Due to global pandemic COVID-19/SARS-CoV-2 associated with spread SARS-CoV-2 virus, difficulty in treating severe cases infection, immunomodulatory activity MSCs due inflammatory microenvironment factors can be used complex tre...

The tissue engineering approach for periodontal regeneration using a combination of stem cells and scaffold has been vastly developed. Mesenchymal Stem Cells (MSCs) seeded with Bovine Teeth Scaffold (BTSc) can repair alveolar bone damage in periodontitis cases. process was analyzed by micro-computed tomography (µ-CT) to observe the structure growth visualize 3-Dimensional (3D). purpose this stu...

Atopic dermatitis (AD) is a chronic cutaneous inflammatory disease caused by an interaction between genetic, immune and epidermal barrier factors. Several treatments can be used to treat this but there are patients that do not respond actual drugs. So, need develop effective therapies for AD. Mesenchymal stem cells (MSCs) non-hematopoietic multipotent adult progenitor with immunomodulatory powe...

Mesenchymal stem cells (MSCs) isolated from dental tissues have also been studied extensively recently due to their relatively easy availability. The researchers working on improving a method for regenerating alveolar bone in patients with cleft lip and palate utilizing mesenchymal human marrow (hBMSCs). A systematic literature review 2010 2022 was performed using PubMed, Medline, ScienceDirect...